FR 50% in pregnancy results in different neuron and glial cell count (astrocytes, olygodendrocytes, and microglia) in the cerebrum and cerebellum of newborn Rattus norvegicus

Objectives: To analyze the difference neuronal and glial (astrocytes, oligodendrocyte, microglia) cell count in cerebrum and cerebellum of Rattus norvegicus newborns with 50% food restriction and control group. Materials and Methods: This was an analytical experimental study with single blind random...

Full description

Saved in:
Bibliographic Details
Main Authors: Fitria Desky, Hermanto Tri Joewono, Widjiati
Format: Article PeerReviewed
Language:English
English
English
Published: Department Obstetrics & Gynecology, Faculty of Medicine, Universitas Airlangga 2019
Subjects:
Online Access:http://repository.unair.ac.id/99246/1/2.%206.%20FR%2050%25%20in%20pregnancy%20results%20in%20different%20neuron%20and%20glial%20cell%20count%20%28astrocytes%2C%20olygodendrocytes%2C%20and%20microgila%29%20in%20the%20cerebrum%20and%20cerebellum%20of%20newborn%20Rattus%20norvegicus.pdf
http://repository.unair.ac.id/99246/2/FR%2050%25%20in%20pregnancy%20results.pdf
http://repository.unair.ac.id/99246/3/FR%2050%25%20in%20pregnancy%20results%20in%20different%20neuron%20and%20glial%20cell%20count.pdf
http://repository.unair.ac.id/99246/
https://e-journal.unair.ac.id/MOG/article/view/15359
http://dx.doi.org/10.20473/mog.V27I22019.56-65
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Universitas Airlangga
Language: English
English
English
id id-langga.99246
record_format dspace
spelling id-langga.992462020-09-27T12:57:20Z http://repository.unair.ac.id/99246/ FR 50% in pregnancy results in different neuron and glial cell count (astrocytes, olygodendrocytes, and microglia) in the cerebrum and cerebellum of newborn Rattus norvegicus Fitria Desky Hermanto Tri Joewono Widjiati R Medicine (General) RG Gynecology and obstetrics Objectives: To analyze the difference neuronal and glial (astrocytes, oligodendrocyte, microglia) cell count in cerebrum and cerebellum of Rattus norvegicus newborns with 50% food restriction and control group. Materials and Methods: This was an analytical experimental study with single blind randomized post test only control group design using animals subjects Rattus norvegicus. This study was conducted at Animal laboratory, Veterinary Faculty, Universitas Airlangga. Animal subjects were divided into FR50% group and control. Neuron and glial (astrocytes, oligodendrocytes, microglia) counts were analyzed using comparison test, with CI 95%. Results: There was a significant difference in cerebrum and cerebellum neuron cell count between intervention and control group (9.88+3.59 vs 16.88+2.553; p=0.000 and 7.5+1.789 vs 11.44+4.56; p=0.02). There was no difference in cerebrum and cerebellum glial cell count. There was a significant difference in cerebellum astrocyte between intervention and control group (80.94+24.255 vs 59.69+18.77; p=0.02) but no difference in cerebrum. There was a significant difference in cerebrum and cerebellum oligodendrocyte between intervention and control group (14.06+12.195 vs 25.13+8.609; p<0.000 and 13.63+6.712 vs 24.00+8.862; p=0.001), and there were significant difference in cerebrum and cerebellum microglia cell between intervention and control group (5.25+3.435 vs 4.94+3.838; p=0.620 and 8.81+4.119 vs 5.25+1.483; p=0.004). Conclusion: Food Restriction 50% (FR50%) in Rattus norvegicus decreased cerebrum and cerebellum neuron cell and oligodendrocyte count and increased cerebrum and cerebellum microglial count. Department Obstetrics & Gynecology, Faculty of Medicine, Universitas Airlangga 2019-12 Article PeerReviewed text en http://repository.unair.ac.id/99246/1/2.%206.%20FR%2050%25%20in%20pregnancy%20results%20in%20different%20neuron%20and%20glial%20cell%20count%20%28astrocytes%2C%20olygodendrocytes%2C%20and%20microgila%29%20in%20the%20cerebrum%20and%20cerebellum%20of%20newborn%20Rattus%20norvegicus.pdf text en http://repository.unair.ac.id/99246/2/FR%2050%25%20in%20pregnancy%20results.pdf text en http://repository.unair.ac.id/99246/3/FR%2050%25%20in%20pregnancy%20results%20in%20different%20neuron%20and%20glial%20cell%20count.pdf Fitria Desky and Hermanto Tri Joewono and Widjiati (2019) FR 50% in pregnancy results in different neuron and glial cell count (astrocytes, olygodendrocytes, and microglia) in the cerebrum and cerebellum of newborn Rattus norvegicus. Majalah Obstetri dan Ginekologi, 27 (2). pp. 56-65. ISSN 08540381 https://e-journal.unair.ac.id/MOG/article/view/15359 http://dx.doi.org/10.20473/mog.V27I22019.56-65
institution Universitas Airlangga
building Universitas Airlangga Library
country Indonesia
collection UNAIR Repository
language English
English
English
topic R Medicine (General)
RG Gynecology and obstetrics
spellingShingle R Medicine (General)
RG Gynecology and obstetrics
Fitria Desky
Hermanto Tri Joewono
Widjiati
FR 50% in pregnancy results in different neuron and glial cell count (astrocytes, olygodendrocytes, and microglia) in the cerebrum and cerebellum of newborn Rattus norvegicus
description Objectives: To analyze the difference neuronal and glial (astrocytes, oligodendrocyte, microglia) cell count in cerebrum and cerebellum of Rattus norvegicus newborns with 50% food restriction and control group. Materials and Methods: This was an analytical experimental study with single blind randomized post test only control group design using animals subjects Rattus norvegicus. This study was conducted at Animal laboratory, Veterinary Faculty, Universitas Airlangga. Animal subjects were divided into FR50% group and control. Neuron and glial (astrocytes, oligodendrocytes, microglia) counts were analyzed using comparison test, with CI 95%. Results: There was a significant difference in cerebrum and cerebellum neuron cell count between intervention and control group (9.88+3.59 vs 16.88+2.553; p=0.000 and 7.5+1.789 vs 11.44+4.56; p=0.02). There was no difference in cerebrum and cerebellum glial cell count. There was a significant difference in cerebellum astrocyte between intervention and control group (80.94+24.255 vs 59.69+18.77; p=0.02) but no difference in cerebrum. There was a significant difference in cerebrum and cerebellum oligodendrocyte between intervention and control group (14.06+12.195 vs 25.13+8.609; p<0.000 and 13.63+6.712 vs 24.00+8.862; p=0.001), and there were significant difference in cerebrum and cerebellum microglia cell between intervention and control group (5.25+3.435 vs 4.94+3.838; p=0.620 and 8.81+4.119 vs 5.25+1.483; p=0.004). Conclusion: Food Restriction 50% (FR50%) in Rattus norvegicus decreased cerebrum and cerebellum neuron cell and oligodendrocyte count and increased cerebrum and cerebellum microglial count.
format Article
PeerReviewed
author Fitria Desky
Hermanto Tri Joewono
Widjiati
author_facet Fitria Desky
Hermanto Tri Joewono
Widjiati
author_sort Fitria Desky
title FR 50% in pregnancy results in different neuron and glial cell count (astrocytes, olygodendrocytes, and microglia) in the cerebrum and cerebellum of newborn Rattus norvegicus
title_short FR 50% in pregnancy results in different neuron and glial cell count (astrocytes, olygodendrocytes, and microglia) in the cerebrum and cerebellum of newborn Rattus norvegicus
title_full FR 50% in pregnancy results in different neuron and glial cell count (astrocytes, olygodendrocytes, and microglia) in the cerebrum and cerebellum of newborn Rattus norvegicus
title_fullStr FR 50% in pregnancy results in different neuron and glial cell count (astrocytes, olygodendrocytes, and microglia) in the cerebrum and cerebellum of newborn Rattus norvegicus
title_full_unstemmed FR 50% in pregnancy results in different neuron and glial cell count (astrocytes, olygodendrocytes, and microglia) in the cerebrum and cerebellum of newborn Rattus norvegicus
title_sort fr 50% in pregnancy results in different neuron and glial cell count (astrocytes, olygodendrocytes, and microglia) in the cerebrum and cerebellum of newborn rattus norvegicus
publisher Department Obstetrics & Gynecology, Faculty of Medicine, Universitas Airlangga
publishDate 2019
url http://repository.unair.ac.id/99246/1/2.%206.%20FR%2050%25%20in%20pregnancy%20results%20in%20different%20neuron%20and%20glial%20cell%20count%20%28astrocytes%2C%20olygodendrocytes%2C%20and%20microgila%29%20in%20the%20cerebrum%20and%20cerebellum%20of%20newborn%20Rattus%20norvegicus.pdf
http://repository.unair.ac.id/99246/2/FR%2050%25%20in%20pregnancy%20results.pdf
http://repository.unair.ac.id/99246/3/FR%2050%25%20in%20pregnancy%20results%20in%20different%20neuron%20and%20glial%20cell%20count.pdf
http://repository.unair.ac.id/99246/
https://e-journal.unair.ac.id/MOG/article/view/15359
http://dx.doi.org/10.20473/mog.V27I22019.56-65
_version_ 1681154067562233856