VALIDITAS CT-SCAN PADA DIAGNOSIS KANKER NASOFARING
Nasopharyngeal cancer (NPC) is the most frequent among head and neck malignant tumor, which has a very high degree of malignancy. CT-scan is chosen in most hospitals as a radiological modality for NPC. The aims of this study was to know the validity of CTscan on diagnosis and evaluation of NPC. A re...
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Main Authors: | , |
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Format: | Theses and Dissertations NonPeerReviewed |
Published: |
[Yogyakarta] : Universitas Gadjah Mada
2012
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Subjects: | |
Online Access: | https://repository.ugm.ac.id/100148/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=56425 |
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Institution: | Universitas Gadjah Mada |
Summary: | Nasopharyngeal cancer (NPC) is the most frequent among head and neck malignant
tumor, which has a very high degree of malignancy. CT-scan is chosen in most hospitals as
a radiological modality for NPC. The aims of this study was to know the validity of CTscan
on diagnosis and evaluation of NPC.
A retrospective observational diagnostic test was conducted to assess the presence
of NPC on CT-scan results, as evidenced by the gold standard of biopsy, between
December 1, 2009 through February 28, 2012 in Sardjito Hospital Yogyakarta. The value
of interobserver agreement from three radiologists who evaluate CT scan for NPC is very
strong. Total of 224 patients consist of 150 men and 74 women, with mean age of 47 years,
showed 93% WHO type III, with the ratio of male and female of 2:1. The validity of entire
CT-scan on NPC had sensitivity 85%, specificity 49%, and accuracy 66%. The highest
sensitivity, specificity and accuracy on MSCT in the diagnosis were 88%, 67% and 83%,
respectively.
The high enough of validity and always found a thickening or a mass in the
nasopharynx, and most of the asymmetry of tubarius torus and fossa Rosenmuller, these
abnormalities on CT-scan could be used as a parameter to determine the diagnosis and
evaluation of NPC. |
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