PENGARUH KADAR CAMPURAN ASAM OLEAT DAN ISOPROPIL ALKOHOL TERHADAP SIFAT FISIK DAN PROFIL TRANSPOR PATCH KALIUM LOSARTAN DENGAN MATRIKS POLIVINIL ALKOHOL DAN POLIVINILPIROLIDON

• Main Authors: , MICHRUN NISA, , Dr. Akhmad Kharis Nugroho, M.Si., Apt
• Format: Theses and Dissertations NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2013
• Subjects: ETD
• Online Access: https://repository.ugm.ac.id/118733/; http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=58707
• Institution: Universitas Gadjah Mada

Delivery of losartan in a transdermal patch dosage form is challengging in terms of formulation due to losartan�s low bioavailability and short elimination. This study aimed to compare and to assess the effects of oleic acid and isopropyl alcohol with concentration of 5% v/v and of 10% v/v in a tr...