KORELASI ANTARA LAJU ENDAP DARAH DENGAN DEFISIT NEUROLOGIS PADA STROKE HEMORAGIK
Background Hemorrhagic stroke is a devastating condition whose mortality rate is significantly high. Neurological worsening in hemorrhagic stroke could arise from primary injury and secondary injury. Secondary injury in hemorrhagic stroke assumed by the process of inflammation response. Previous stu...
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2013
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id-ugm-repo.1192692016-03-04T08:43:43Z https://repository.ugm.ac.id/119269/ KORELASI ANTARA LAJU ENDAP DARAH DENGAN DEFISIT NEUROLOGIS PADA STROKE HEMORAGIK , Suryo Bantolo , Prof. Dr. dr. Sri Sutarni, SpS(K) ETD Background Hemorrhagic stroke is a devastating condition whose mortality rate is significantly high. Neurological worsening in hemorrhagic stroke could arise from primary injury and secondary injury. Secondary injury in hemorrhagic stroke assumed by the process of inflammation response. Previous studies stated that inflammation influences the neurological deficit that occurred. Hence, novel approach of management aimed to alleviate the inflammation. To measure level of inflammation level, several biomarker are used. Erythrocyte Sedimentation Rate (ESR) is one of inflammation biomarker that is expected can disclose magnitude of inflammation process that progressed in stroke hemorrhagic. This research would like to study the correlation of neurological deficits in hemorrhagic stroke patients and the level of ESR. Method This study used a cross sectional design with consecutive sampling technic. Each subject was asked to sign informed consent. The study was conducted on admission to the Dr. Sardjito hospital and all patients were receiving treatment for hemorrhagic stroke. Statistical analysis for each variable is using pearson�s test for parametric and spearman�s for non-parametric data. The results of bivariate analysis followed by multivariate analysis with linear regression. Result and discussion Correlation of Erythrocyte Sedimentation Rate and Neurological Deficits in Hemorrhagic Stroke Suryo Bantolo*, Sri Sutarni**, Abdul Gofir** *Resident of Neurology Departement FK-UGM/ Dr.Sardjito Hospital **Senior Staf of Neurology Departement FK-UGM/ Dr.Sardjito Hospital The study was conducted in June-August 2012 at Neurology deparment Dr Sardjito Hospital. Achieved total of 42 subjects, 22 men, 20 women. Based on statistical analysis, no significant correlation between erythrocyte sedimentation rate with neurological deficits which examined with Gadjah Mada Stroke Scale in patients with hemorrhagic stroke. This is possibly because the erythrocyte sedimentation rate examination performed at the onset of the attack, before the inflammatory reaction that occurs on the fifth day. There may also be due to a polymorphism in subjects that increased cytokine response does not occur. The weakness of this study is not examining the liver function where the synthesis of fibrinogen that affects erythrocyte sedimentation rate occurs. Conclusion In this study there was no correlation between erythrocyte sedimentation rate with neurological deficits were examined with Gadjah Mada Stroke Scale in patients with hemorrhagic stroke. [Yogyakarta] : Universitas Gadjah Mada 2013 Thesis NonPeerReviewed , Suryo Bantolo and , Prof. Dr. dr. Sri Sutarni, SpS(K) (2013) KORELASI ANTARA LAJU ENDAP DARAH DENGAN DEFISIT NEUROLOGIS PADA STROKE HEMORAGIK. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=59264 |
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ETD , Suryo Bantolo , Prof. Dr. dr. Sri Sutarni, SpS(K) KORELASI ANTARA LAJU ENDAP DARAH DENGAN DEFISIT NEUROLOGIS PADA STROKE HEMORAGIK |
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Background
Hemorrhagic stroke is a devastating condition whose mortality rate is significantly high.
Neurological worsening in hemorrhagic stroke could arise from primary injury and secondary
injury. Secondary injury in hemorrhagic stroke assumed by the process of inflammation
response. Previous studies stated that inflammation influences the neurological deficit that
occurred. Hence, novel approach of management aimed to alleviate the inflammation. To
measure level of inflammation level, several biomarker are used. Erythrocyte Sedimentation
Rate (ESR) is one of inflammation biomarker that is expected can disclose magnitude of
inflammation process that progressed in stroke hemorrhagic. This research would like to study
the correlation of neurological deficits in hemorrhagic stroke patients and the level of ESR.
Method
This study used a cross sectional design with consecutive sampling technic. Each subject was
asked to sign informed consent. The study was conducted on admission to the Dr. Sardjito
hospital and all patients were receiving treatment for hemorrhagic stroke. Statistical analysis for
each variable is using pearson�s test for parametric and spearman�s for non-parametric data. The
results of bivariate analysis followed by multivariate analysis with linear regression.
Result and discussion
Correlation of Erythrocyte Sedimentation Rate and Neurological Deficits in Hemorrhagic
Stroke
Suryo Bantolo*, Sri Sutarni**, Abdul Gofir**
*Resident of Neurology Departement FK-UGM/ Dr.Sardjito Hospital
**Senior Staf of Neurology Departement FK-UGM/ Dr.Sardjito Hospital
The study was conducted in June-August 2012 at Neurology deparment Dr Sardjito Hospital.
Achieved total of 42 subjects, 22 men, 20 women. Based on statistical analysis, no significant
correlation between erythrocyte sedimentation rate with neurological deficits which examined
with Gadjah Mada Stroke Scale in patients with hemorrhagic stroke. This is possibly because the
erythrocyte sedimentation rate examination performed at the onset of the attack, before the
inflammatory reaction that occurs on the fifth day. There may also be due to a polymorphism in
subjects that increased cytokine response does not occur. The weakness of this study is not
examining the liver function where the synthesis of fibrinogen that affects erythrocyte
sedimentation rate occurs.
Conclusion
In this study there was no correlation between erythrocyte sedimentation rate with neurological
deficits were examined with Gadjah Mada Stroke Scale in patients with hemorrhagic stroke. |
format |
Theses and Dissertations NonPeerReviewed |
author |
, Suryo Bantolo , Prof. Dr. dr. Sri Sutarni, SpS(K) |
author_facet |
, Suryo Bantolo , Prof. Dr. dr. Sri Sutarni, SpS(K) |
author_sort |
, Suryo Bantolo |
title |
KORELASI ANTARA LAJU ENDAP DARAH DENGAN DEFISIT NEUROLOGIS PADA STROKE HEMORAGIK |
title_short |
KORELASI ANTARA LAJU ENDAP DARAH DENGAN DEFISIT NEUROLOGIS PADA STROKE HEMORAGIK |
title_full |
KORELASI ANTARA LAJU ENDAP DARAH DENGAN DEFISIT NEUROLOGIS PADA STROKE HEMORAGIK |
title_fullStr |
KORELASI ANTARA LAJU ENDAP DARAH DENGAN DEFISIT NEUROLOGIS PADA STROKE HEMORAGIK |
title_full_unstemmed |
KORELASI ANTARA LAJU ENDAP DARAH DENGAN DEFISIT NEUROLOGIS PADA STROKE HEMORAGIK |
title_sort |
korelasi antara laju endap darah dengan defisit neurologis pada stroke hemoragik |
publisher |
[Yogyakarta] : Universitas Gadjah Mada |
publishDate |
2013 |
url |
https://repository.ugm.ac.id/119269/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=59264 |
_version_ |
1681231113204269056 |