Faktor Prediktor Ketidakcapaian Kadar LDL (Low Density Lipoprotein) pada Pasien Stroke Iskemik yang Menggunakan Statin

• Main Authors: , Amelia Rumi, , Prof. Agung Endro Nugroho, M.Si., Ph.D., Apt.
• Format: Theses and Dissertations NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2013
• Subjects: ETD
• Online Access: https://repository.ugm.ac.id/120845/; http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=60883
• Institution: Universitas Gadjah Mada

Background: Stroke is the highest cause of disability and death in the world. Based on data collected stroke foundation Indonesia, the number of stroke patients in Indonesia was ranked first in Asia with stroke incidence of the most common is an ischemic stroke. Ischemic stroke occurs due to the resistance of the blood vessels in the brain. The bottleneck caused by the formation of atherosclerosis. High levels of LDL are thought to affect the formation of atherosclerosis. High levels of LDL lead to the use of statins in patients with ischemic stroke to be quite high. Statins are expected to work to reduce levels of LDL and decreased the formation of atherosclerotic in patients of ischemic stroke. Objective: To determine factors that affect the prevalence predictor factors close to the levels LDL (Low Density Lipoprotein) in patients of ischemic stroke in treated with statins. Methods: This study is an analytical study by the research design used a nested case-control method. The samples in this study were in patients of ischemic stroke in treated statins and met the inclusion criteria. Patients were classified into groups of cases if the medical record search results and registers stroke patients showed LDL levels >100 mg/dL. Whereas ischemic stroke patients with LDL levels <100 mg/dL are classified into the control group. The result tracking medical records and stroke registers then analyzed by bivariate and multivariate analyzes. Results: A total of 236 ischemic stroke patients met the inclusion criteria. The result is patients with very high LDL (p = 0,006