PENGARUH PEMBERIAN TOKSOPLASMANUUR DAN INTERTRIM ® LA TERHADAP GAMBARAN HISTOPATOLOGI HATI DAN PARU MENCIT (Mus musculus) YANG DIINFEKSI Toxoplasma gondii

• Main Authors: , DEWI SUCI ARISTYANTI, , drh. Dwi Priyowidodo, M.P.
• Format: Theses and Dissertations NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2013
• Subjects: ETD
• Online Access: https://repository.ugm.ac.id/121218/; http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=61290
• Institution: Universitas Gadjah Mada

Toxoplasmosis is parasit�s disease that caused by Toxoplasma gondii and zoonotic. The purpose of this research is to obtain the Toksoplasmanuur and Intertrim® LA effect in relation to liver and lungs histopthalogy that infected by T. gondii. Twenty four mice used and devided into four groups. First group (K.I) was the control uninfected group, there were six mice used, second group (K.II) as the control group infected by T. gondii, there were four mice used, and third group (K.III) were infected by T. gondii and threat by Toksoplamanuur 8 mg/ day/mice orally, and fourth group (K.IV) were infected by T. gondii and threat by Intertrim® LA 0,02 ml/day/ mice orally. The mice were infected by T. gondii�s tachyzoit 1x103 intraperitoneally at the first day. Histopthalogy examination were taken from mice�s organs which has the longest life. Liver and lungs were taken to 10% formalin for histopathology analysis. Obtained data were analyzed descriptively and the result show that Toksoplasmanuur cant�t reduce the liver and lungs destruction caused by T. gondii. The result showed that Intertrim® LA can reduce the liver and lungs destruction caused by T.gondii and increase the living ability of the mice. The conclusion of this research showed that Toksoplasmanuur are not effective and Intertrim® LA are effective to cure the toxoplasmosis.