GAMBARAN MIKROSKOPIK KESEMBUHAN JARINGAN LUKA KULIT ANJING (Canis familiaris) YANG DITERAPI SALEP EKSTRAK ETANOL DAUN BINAHONG (Anredera cordifolia (Ten.) Steenis) HARI KE- 14

• Main Authors: , MUHAMMAD ARIF BASKORO, , drh. Agus Budi Santosa, MS.
• Format: Theses and Dissertations NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2013
• Subjects: ETD
• Online Access: https://repository.ugm.ac.id/121816/; http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=61914
• Institution: Universitas Gadjah Mada

Dog (Canis familiaris) is a pet that should be given attention and outpouring of affection. Dogs may experience injury or wound. One of herbal that is widely used as wound medicine is binahong (Anredera cordifolia (Ten) Steenis). The purpose of this research was to determine the microscopic description of fibroblast cells and leukocytes in the incision wound of dog skin who where treated white the ointment ethanol extract of binahong leaves concentration of 5% and 10% are microscopic. Four local female dogs used in this study. Prior research adapted to any dog for a few days and were given ivermectin worming. Making a incisionmade after adaptation is completed as much as 3 slices (A, B, and C) on each dog on the left side of the abdomen in the vertical direction. A incision of group A as the control, untreatment, a incision of group B was given the ointment binahong leaf extract 5% ethanol extraction and a incision of group C was given an ointment binahong leaf extract 10% ethanol extraction. On day 14 most of the wound healing tissue samples taken measuring 2x2 cm, then put into 10% formalin solution for histological examination. The tissue sample is sent to the Mikroanatomi Laboratory of the Faculty of Veterinary Medicine to made preparations for histology with Haematoxylin-Eosin staining (HE). Display leukocyte and fibroblast cells was calculated and analyzed using ANOVA test with significance level p < 0.05. Results of microscopic examination of fibroblast and leukocyte cell numbers in group B and group C less than in group A. Statistical analysis using ANOVA showed no significant difference between the control group and lubrication binahong leaf extract (5% and 10%). These results can be concluded that the description of the wound healing canine skin slices treated with the ointment of binahong leaves ethanol extract had healed.