PENGARUH PEMBERIAN BUBUK TULANG AYAM PADA INDUK TIKUS Sprague dawley SELAMA MASA KEHAMILAN DAN MENYUSUI TERHADAP KETEBALAN DENTIN GIGI ANAKAN

• Main Authors: , HERIATI SITOSARI, , drg. Alma Linggar Jonarta, M.Kes.
• Format: Theses and Dissertations NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2013
• Subjects: ETD
• Online Access: https://repository.ugm.ac.id/122138/; http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=62238
• Institution: Universitas Gadjah Mada

Nutritional deficiency during pregnancy may impair children�s tooth formation. Chicken bones contains various proteins and minerals that can be used as an additional nutrient provider. The purpose of this study was to determine the effect of chicken bone powder administered on Sprague dawley rats during pregnancy and lactation on pups� dentin thickness. Nine Sprague dawley female rats aged 10-12 weeks with approximately weight 200-250 g were divided into 2 groups: a control group consisted of a sub-group of negative control (A) and comparator (B), and a treatment group (C). Since the first day of pregnancy until the pups were 5 days old, each sub group and group were intragastric administered with 2 ml of suspension per day. Suspension of 2,5% CMC-Na, 1,5% of multivitamins and minerals, and 13,75% of chicken bone powder was given to group A, B, and C, consecutively. At the age of 5 days old, four rat pups of each group were sacrificed, the mandibles were collected, histologicaly processed, and stained with HE. The observation of the first molar tooth dentin thickness was done under light microscope in the magnification of 100 x. The data was analyzed using ANOVA and LSD post-hoc test (p<0,05). The administration of chicken bone powder during pregnancy and lactation on the mother rats showed a significant effect to the pup�s dentin thickness. It is concluded that the administration of chicken powder in mother rats during pregnancy and lactation may increase the thickness of dentin on rat pups.