KORELASI ANTARA KADAR VITAMIN C DALAM SERUM DENGAN DERAJAT KEPARAHAN AKNE VULGARIS DI YOGYAKARTA
Background: Acne vulgaris is the most common skin disease that occurs in adolescence. Commonly, the pathogenesis of acne vulgaris is caused by free radicals belonging to the reactive oxygen species (ROS). ROS is needed to maintain the physiological function of the body, but when it excesses in quant...
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[Yogyakarta] : Universitas Gadjah Mada
2013
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id-ugm-repo.1230932016-03-04T08:42:20Z https://repository.ugm.ac.id/123093/ KORELASI ANTARA KADAR VITAMIN C DALAM SERUM DENGAN DERAJAT KEPARAHAN AKNE VULGARIS DI YOGYAKARTA , RICKY ARIS FANDIKA , dr. Kristiana Etnawati, MPH, Sp.KK (K) ETD Background: Acne vulgaris is the most common skin disease that occurs in adolescence. Commonly, the pathogenesis of acne vulgaris is caused by free radicals belonging to the reactive oxygen species (ROS). ROS is needed to maintain the physiological function of the body, but when it excesses in quantity, oxidative stress happens leading to an inflammatory response that manifests differently in each individual. Oxidative stress is neutralized by antioxidant, including vitamin C or ascorbic acid. Administration of vitamin C and its derivatives, either through oral or topical has been shown to reduce level of oxidative stress in the body. Serum level of vitamin C in higher in people who do not suffer from acne vulgaris compared with patients with acne vulgaris has been proven true. However, serum level of vitamin C in various degrees of severity in patients with acne vulgaris has not been performed. Objective: To find the correlation between serum level of vitamin C in various degrees of severity of acne vulgaris. Method: This study used cross-sectional involving 51 respondents with acne vulgaris with various degrees of severity entry criteria for inclusion. We used DNPH principle to measure serum levels of vitamin C. The result is analyzed with Pearson correlation analysis test methods. Result: The value of correlation is -0,405 (r = -0,405) between serum levels of vitamin C and degrees of severity of acne vulgaris. This study is also statistically significant (p = 0,003, p < 0,05). Conclusion: There is a correlation between serum levels of vitamin C and degrees of severity of acne vulgaris. The strength of correlation is moderate and negative correlation direction means if the value of serum levels of vitamin C is greater, so the degree of severity of acne vulgaris would be milder and vice versa. [Yogyakarta] : Universitas Gadjah Mada 2013 Thesis NonPeerReviewed , RICKY ARIS FANDIKA and , dr. Kristiana Etnawati, MPH, Sp.KK (K) (2013) KORELASI ANTARA KADAR VITAMIN C DALAM SERUM DENGAN DERAJAT KEPARAHAN AKNE VULGARIS DI YOGYAKARTA. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=63204 |
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ETD , RICKY ARIS FANDIKA , dr. Kristiana Etnawati, MPH, Sp.KK (K) KORELASI ANTARA KADAR VITAMIN C DALAM SERUM DENGAN DERAJAT KEPARAHAN AKNE VULGARIS DI YOGYAKARTA |
description |
Background: Acne vulgaris is the most common skin
disease that occurs in adolescence. Commonly, the
pathogenesis of acne vulgaris is caused by free
radicals belonging to the reactive oxygen species
(ROS). ROS is needed to maintain the physiological
function of the body, but when it excesses in quantity,
oxidative stress happens leading to an inflammatory
response that manifests differently in each individual.
Oxidative stress is neutralized by antioxidant,
including vitamin C or ascorbic acid. Administration of
vitamin C and its derivatives, either through oral or
topical has been shown to reduce level of oxidative
stress in the body. Serum level of vitamin C in higher
in people who do not suffer from acne vulgaris compared
with patients with acne vulgaris has been proven true.
However, serum level of vitamin C in various degrees of
severity in patients with acne vulgaris has not been
performed.
Objective: To find the correlation between serum level
of vitamin C in various degrees of severity of acne
vulgaris.
Method: This study used cross-sectional involving 51
respondents with acne vulgaris with various degrees of
severity entry criteria for inclusion. We used DNPH
principle to measure serum levels of vitamin C. The
result is analyzed with Pearson correlation analysis
test methods.
Result: The value of correlation is -0,405 (r = -0,405)
between serum levels of vitamin C and degrees of
severity of acne vulgaris. This study is also
statistically significant (p = 0,003, p < 0,05).
Conclusion: There is a correlation between serum levels
of vitamin C and degrees of severity of acne vulgaris.
The strength of correlation is moderate and negative
correlation direction means if the value of serum
levels of vitamin C is greater, so the degree of
severity of acne vulgaris would be milder and vice
versa. |
format |
Theses and Dissertations NonPeerReviewed |
author |
, RICKY ARIS FANDIKA , dr. Kristiana Etnawati, MPH, Sp.KK (K) |
author_facet |
, RICKY ARIS FANDIKA , dr. Kristiana Etnawati, MPH, Sp.KK (K) |
author_sort |
, RICKY ARIS FANDIKA |
title |
KORELASI ANTARA KADAR VITAMIN C DALAM SERUM DENGAN DERAJAT KEPARAHAN AKNE VULGARIS DI YOGYAKARTA |
title_short |
KORELASI ANTARA KADAR VITAMIN C DALAM SERUM DENGAN DERAJAT KEPARAHAN AKNE VULGARIS DI YOGYAKARTA |
title_full |
KORELASI ANTARA KADAR VITAMIN C DALAM SERUM DENGAN DERAJAT KEPARAHAN AKNE VULGARIS DI YOGYAKARTA |
title_fullStr |
KORELASI ANTARA KADAR VITAMIN C DALAM SERUM DENGAN DERAJAT KEPARAHAN AKNE VULGARIS DI YOGYAKARTA |
title_full_unstemmed |
KORELASI ANTARA KADAR VITAMIN C DALAM SERUM DENGAN DERAJAT KEPARAHAN AKNE VULGARIS DI YOGYAKARTA |
title_sort |
korelasi antara kadar vitamin c dalam serum dengan derajat keparahan akne vulgaris di yogyakarta |
publisher |
[Yogyakarta] : Universitas Gadjah Mada |
publishDate |
2013 |
url |
https://repository.ugm.ac.id/123093/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=63204 |
_version_ |
1681231826335563776 |