PENGARUH APLIKASI TOPIKAL CASEIN PHOSPHOPEPTIDE AMORPHOUS CALCIUM PHOSPHATE (CPP-ACP) TERHADAP PERTUMBUHAN Streptococcus alpha DAN AKUMULASI PLAK GIGI

• Main Authors: , Maria Andrini, , Dr.drg. Indah Titien S, SU, Sp.KGA (K).
• Format: Theses and Dissertations NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2013
• Subjects: ETD
• Online Access: https://repository.ugm.ac.id/123155/; http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=63266
• Institution: Universitas Gadjah Mada

Plaque is one of the causes of oral disease in children. This plaque needs to be controlled mechanically and chemically. One of chemical plaque control is a topical application that contains casein. Casein-Amorphous Calcium Phosphate Phospopeptide (CPP-ACP) is a substance can inhibit the attachment of bacteria plaque on the teeth. We expect that it will inhibit the growth of alpha- Streptococcus so that plaque acumulation also decrease. The aim of this study is to investigate the influence of topical application of CPP-ACP to the growth of alpha-Streptococcus and dental plaque acumulation. The study subjects consisted of 22 children, aged 3-6 years. Topical application of CPP-ACP was once a day, before bedtime, in 28 days. Data the growth of alpha-Streptococcus was performed by swabbing plaque in the buccal surfaces of maxillary and mandibulary teeth with sterilized cotton bud then inoculated for 24 hours. The plaque score were measured by PHPM methods (Podshadley and Haley, 1968, modification Amith et al., 2007). Measuring the growth of alpha-Streptococcus and the plaque score taken before, after 7, 14, 28 days the application. Data were analyzed by Repeated ANOVA resumed Pair Wise Comparison (LSD). The result showed that the growth of alpha-Streptococcus before topical application of CPP-ACP was highest (549,45.104±146,608.104 CFU/ml), after 28 days application was lowest (142,18.104±26,005.104 CFU/ml). The plaque score before topical application was highest (4.1182 ± 1.01589), after 28 days application was lowest (2.2682 ± .45918). The result of Repeated ANOVA resumed Pair Wise Comparison (LSD) showed that those were significant differences (p<0.05). In conclusion, the more frequent topical application of CPPACP, the lowest growth of alpha-Streptococcus and plaque acumulation.