Efek Ekstrak Etanolik Batang Kareumbi (Homalanthus populneus (Geisel.) Pax) terhadap Proliferasi dan Sitotoksisitas Human Peripheral Blood Mononuclear Cells (PBMC) dan Makrofag Mencit (Mus musculus L.)

The ethanolic extract of Homalanthus populneus contains a unique phorbolester called prostratin. Prostratin has an anti-viral activity and cytoprotective effect on monocyte, macrophage, and T cells infected by HIV-1. This study aims to determine the activity of ethanolic extract of Homalanthus popul...

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Bibliographic Details
Main Authors: , EVARIANTI, , Dr. biol. hom. Nastiti Wijayanti, S.Si., M.Si.
Format: Theses and Dissertations NonPeerReviewed
Published: [Yogyakarta] : Universitas Gadjah Mada 2013
Subjects:
ETD
Online Access:https://repository.ugm.ac.id/125157/
http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=65322
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Institution: Universitas Gadjah Mada
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Summary:The ethanolic extract of Homalanthus populneus contains a unique phorbolester called prostratin. Prostratin has an anti-viral activity and cytoprotective effect on monocyte, macrophage, and T cells infected by HIV-1. This study aims to determine the activity of ethanolic extract of Homalanthus populneus (Geisel.) Pax�s stems on human peripheral blood mononuclear cell (PBMC) and mice macrophages. The cytotoxicity effect of ethanolic extract of H. populneus was assessed using the MTT assay. There were a control group, solvent control (DMSO 0.125 % and 0.25 %), positive control (Lipopolysaccharides (LPS) 1, 10, 50 mg/mL for macrophages), and an extract treatment group (7.8125