HIPERGLIKEMIA DALAM 24 JAM PERTAMA PERAWATAN SEBAGAI FAKTOR PROGNOSIS LUARAN KLINIS PASIEN KRITIS DI PICU

• Main Authors: , LUCIANA INTANTI PUTRIJAYA, , dr. Nenny Sri Mulyani, SpA(K)
• Format: Theses and Dissertations NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2013
• Subjects: ETD
• Online Access: https://repository.ugm.ac.id/126276/; http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=66488
• Institution: Universitas Gadjah Mada

Several studies showed that hyperglycemia is common in critically ill children and associated with poor clinical outcomes. However these findings are still inconsistent. This study was conducted to identify whether hyperglycemia within the first 24 hours of hospitalization is a prognostic factor for PICU mortality and length of stay. This was a retrospective cohort study. Subjects were children aged 1 month- 18 years hospitalized at PICU Dr. Sardjito General Hospital from February 2009 to January 2011, with no history of diabetes mellitus and administration of insulin. Data of the highest blood glucose levels within the first 24 hours,PRISM III score, nutritional status, surgical/medical case, external factors affecting the incidence of hyperglycemia (exogenous glucocorticoids, exogenous catecholamines, diuretics, intravenous dextrose), mortality and length of stay, were collected from medical records. Subjects were divided into two blood glucose level group: >150 mg/dL (hyperglycemia) and 80-150 mg/dL (normoglycemia). Of the 190 eligible subjects (95 subjects in each blood glucose level group), 32,6% died in PICU. Mortality was higher in subjects with blood glucose levels >150 mg/dL compared to 80-150 mg/dL (35.8% vs 29.5%), but the association was not significant (RR 1.2, 95%CI 0.8 to1.8