UJI AKTIVITAS SITOTOKSIK SENYAWA 7-O-PROPIL 3�,4�- DIMETOKSIISOFLAVON HASIL SINTESIS PADA KULTUR SEL KANKER PAYUDARA MCF-7 DAN T47D

Background: Cancer is an illness with high incidence and high morbidity. Isoflavon is a compound of natural substance that can prevent many kind of chronic illness, especially cancer. A compound of 7-O-Propil 3�, 4� Dimethoxyisoflavon is a new compound which is derived from isoflavon, but the cy...

Full description

Saved in:
Bibliographic Details
Main Authors: , ELFIAN YOGY FISTA, , Dra. Sri Herwiyanti,M.S.
Format: Theses and Dissertations NonPeerReviewed
Published: [Yogyakarta] : Universitas Gadjah Mada 2014
Subjects:
ETD
Online Access:https://repository.ugm.ac.id/128036/
http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=68362
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Universitas Gadjah Mada
Description
Summary:Background: Cancer is an illness with high incidence and high morbidity. Isoflavon is a compound of natural substance that can prevent many kind of chronic illness, especially cancer. A compound of 7-O-Propil 3�, 4� Dimethoxyisoflavon is a new compound which is derived from isoflavon, but the cytotoxic activity of this compound on cancer cell is not known. Objective: This experiment was intended to know the cytotoxic activity of 7-O-Propil 3�, 4� Dimethoxyisoflavon which is isoflavone derivate compound on cell line culture of breast cancer MCF-7 and T47D. Method: This research was a quasi-experimental study using cell line culture of breast cancer MCF-7 and T47D. The experimental group was 7-propa ISR while doxorubicin was the control group. Cytotoxicity test used MTT assay method. Experimental compound in various concentration 6,25