PENGARUH PEMBERIAN EKSTRAK ETANOL PEGAGAN (Centella asiatica sp.) TERHADAP MEMORI PASCASTRES LISTRIK KRONIK Kajian pada Tikus Putih (Sprague dawley) dengan Dosis 150 mg/kgBB dan 300 mg/kgBB selama Empat Minggu dengan Parameter Waktu (Escape Latency Time) pada Uji Morris Water Maze

PENGARUH PEMBERIAN EKSTRAK ETANOL PEGAGAN (Centella asiatica sp.) TERHADAP MEMORI PASCASTRES LISTRIK KRONIK Kajian pada Tikus Putih (Sprague dawley) dengan Dosis 150 mg/kgBB dan 300 mg/kgBB selama Empat Minggu dengan Parameter Waktu (Escape Latency Time) pada Uji Morris Water Maze

Background: Pegagan has neurotropic and neuroprotective effects. Objective: To know the effect of pegagan (Centella asiatica sp.) in improving memory after electrical stress induction. Materials and Methods: This study used pre and post controled group design. Fifthteen male rats (Sprague dawley), a...

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Main Authors: , SHINTA SEPTIARINA, , dr. Dwi Cahyani Ratna Sari, M.Kes,.P.A (K)
Format: Theses and Dissertations NonPeerReviewed
Published: [Yogyakarta] : Universitas Gadjah Mada 2014
Subjects:
ETD
Online Access:https://repository.ugm.ac.id/128354/
http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=68694
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spelling id-ugm-repo.1283542016-03-04T08:12:31Z https://repository.ugm.ac.id/128354/ PENGARUH PEMBERIAN EKSTRAK ETANOL PEGAGAN (Centella asiatica sp.) TERHADAP MEMORI PASCASTRES LISTRIK KRONIK Kajian pada Tikus Putih (Sprague dawley) dengan Dosis 150 mg/kgBB dan 300 mg/kgBB selama Empat Minggu dengan Parameter Waktu (Escape Latency Time) pada Uji Morris Water Maze , SHINTA SEPTIARINA , dr. Dwi Cahyani Ratna Sari, M.Kes,.P.A (K) ETD Background: Pegagan has neurotropic and neuroprotective effects. Objective: To know the effect of pegagan (Centella asiatica sp.) in improving memory after electrical stress induction. Materials and Methods: This study used pre and post controled group design. Fifthteen male rats (Sprague dawley), aged 4 weeks and ±100 gram weight were divided randomly into 3 groups, two treated groups and one controled group. Treated groups were given ethanolic extract of pegagan with doses of 150 mg/KgBB (KP1) and 300 mg/kgBB (KP2), and controled group was given aquades(KN) by oral for 28 days. Every rats were given electrical stress induction for 10 minutes every day. The rats were tested with Morris Water Maze (MWM) twice daily for 6 days. The scoring parameter of rats performance was based on the average time taken to reach the platform (escape latency time). Kruskal-Walish test was used to know the differences of memory between treated and controled group. Result: The results showed that the average of escape latency time in rats KN, KP1, KP2 groups were 8,77±0,297 [Yogyakarta] : Universitas Gadjah Mada 2014 Thesis NonPeerReviewed , SHINTA SEPTIARINA and , dr. Dwi Cahyani Ratna Sari, M.Kes,.P.A (K) (2014) PENGARUH PEMBERIAN EKSTRAK ETANOL PEGAGAN (Centella asiatica sp.) TERHADAP MEMORI PASCASTRES LISTRIK KRONIK Kajian pada Tikus Putih (Sprague dawley) dengan Dosis 150 mg/kgBB dan 300 mg/kgBB selama Empat Minggu dengan Parameter Waktu (Escape Latency Time) pada Uji Morris Water Maze. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=68694
institution Universitas Gadjah Mada
building UGM Library
country Indonesia
collection Repository Civitas UGM
topic ETD
spellingShingle ETD
, SHINTA SEPTIARINA
, dr. Dwi Cahyani Ratna Sari, M.Kes,.P.A (K)
PENGARUH PEMBERIAN EKSTRAK ETANOL PEGAGAN (Centella asiatica sp.) TERHADAP MEMORI PASCASTRES LISTRIK KRONIK Kajian pada Tikus Putih (Sprague dawley) dengan Dosis 150 mg/kgBB dan 300 mg/kgBB selama Empat Minggu dengan Parameter Waktu (Escape Latency Time) pada Uji Morris Water Maze
description Background: Pegagan has neurotropic and neuroprotective effects. Objective: To know the effect of pegagan (Centella asiatica sp.) in improving memory after electrical stress induction. Materials and Methods: This study used pre and post controled group design. Fifthteen male rats (Sprague dawley), aged 4 weeks and ±100 gram weight were divided randomly into 3 groups, two treated groups and one controled group. Treated groups were given ethanolic extract of pegagan with doses of 150 mg/KgBB (KP1) and 300 mg/kgBB (KP2), and controled group was given aquades(KN) by oral for 28 days. Every rats were given electrical stress induction for 10 minutes every day. The rats were tested with Morris Water Maze (MWM) twice daily for 6 days. The scoring parameter of rats performance was based on the average time taken to reach the platform (escape latency time). Kruskal-Walish test was used to know the differences of memory between treated and controled group. Result: The results showed that the average of escape latency time in rats KN, KP1, KP2 groups were 8,77±0,297
format Theses and Dissertations
NonPeerReviewed
author , SHINTA SEPTIARINA
, dr. Dwi Cahyani Ratna Sari, M.Kes,.P.A (K)
author_facet , SHINTA SEPTIARINA
, dr. Dwi Cahyani Ratna Sari, M.Kes,.P.A (K)
author_sort , SHINTA SEPTIARINA
title PENGARUH PEMBERIAN EKSTRAK ETANOL PEGAGAN (Centella asiatica sp.) TERHADAP MEMORI PASCASTRES LISTRIK KRONIK Kajian pada Tikus Putih (Sprague dawley) dengan Dosis 150 mg/kgBB dan 300 mg/kgBB selama Empat Minggu dengan Parameter Waktu (Escape Latency Time) pada Uji Morris Water Maze
title_short PENGARUH PEMBERIAN EKSTRAK ETANOL PEGAGAN (Centella asiatica sp.) TERHADAP MEMORI PASCASTRES LISTRIK KRONIK Kajian pada Tikus Putih (Sprague dawley) dengan Dosis 150 mg/kgBB dan 300 mg/kgBB selama Empat Minggu dengan Parameter Waktu (Escape Latency Time) pada Uji Morris Water Maze
title_full PENGARUH PEMBERIAN EKSTRAK ETANOL PEGAGAN (Centella asiatica sp.) TERHADAP MEMORI PASCASTRES LISTRIK KRONIK Kajian pada Tikus Putih (Sprague dawley) dengan Dosis 150 mg/kgBB dan 300 mg/kgBB selama Empat Minggu dengan Parameter Waktu (Escape Latency Time) pada Uji Morris Water Maze
title_fullStr PENGARUH PEMBERIAN EKSTRAK ETANOL PEGAGAN (Centella asiatica sp.) TERHADAP MEMORI PASCASTRES LISTRIK KRONIK Kajian pada Tikus Putih (Sprague dawley) dengan Dosis 150 mg/kgBB dan 300 mg/kgBB selama Empat Minggu dengan Parameter Waktu (Escape Latency Time) pada Uji Morris Water Maze
title_full_unstemmed PENGARUH PEMBERIAN EKSTRAK ETANOL PEGAGAN (Centella asiatica sp.) TERHADAP MEMORI PASCASTRES LISTRIK KRONIK Kajian pada Tikus Putih (Sprague dawley) dengan Dosis 150 mg/kgBB dan 300 mg/kgBB selama Empat Minggu dengan Parameter Waktu (Escape Latency Time) pada Uji Morris Water Maze
title_sort pengaruh pemberian ekstrak etanol pegagan (centella asiatica sp.) terhadap memori pascastres listrik kronik kajian pada tikus putih (sprague dawley) dengan dosis 150 mg/kgbb dan 300 mg/kgbb selama empat minggu dengan parameter waktu (escape latency time) pada uji morris water maze
publisher [Yogyakarta] : Universitas Gadjah Mada
publishDate 2014
url https://repository.ugm.ac.id/128354/
http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=68694
_version_ 1681232779520507904

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