ANALISIS FARMAKOLOGI DAN EPIDEMIOLOGI RESIDU DELTAMETRIN PADA DAGING BROILER DI WILAYAH KABUPATEN SLEMAN DAERAH ISTIMEWA YOGYAKARTA
Pesticide residue in the meat and liver of broiler causes troubles for consumers in getting safe, healthy, whole, and halal nutrients. This research was aimed to carry out an optimization and validation of deltamethrin analysis procedure by using high performance liquid chr...
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id-ugm-repo.1307322016-03-04T08:07:43Z https://repository.ugm.ac.id/130732/ ANALISIS FARMAKOLOGI DAN EPIDEMIOLOGI RESIDU DELTAMETRIN PADA DAGING BROILER DI WILAYAH KABUPATEN SLEMAN DAERAH ISTIMEWA YOGYAKARTA , R. Gagak Donny Satria , Prof. Dr. drh. Bambang Sumiarto, S.U., M.Sc. ETD Pesticide residue in the meat and liver of broiler causes troubles for consumers in getting safe, healthy, whole, and halal nutrients. This research was aimed to carry out an optimization and validation of deltamethrin analysis procedure by using high performance liquid chromatography (HPLC), based on specification of parameter, precision, accuracy, limit of quantification, linearity, and confirmation of the compliance level by using Kappa test. The other aim of this research was to carry out the pharmacology experiment on deltamethrin residue in the meat of broiler that had been fed with different dosages of deltamethrin orally and analyzed its correlation between treatment and concentration found in the specimens. Research on prevalence and situation description of deltamethrin residue in meat of broiler at the district of Kabupaten Sleman, including the the possible associated factors, was carried out by using epidemiology study. The main equipment used for the residue analysis in tissue was HPLC with the appropriate procedure. The research consisted of the stage of validation and suitability analysis, experimental stage, and field research. Samples that were used for validation analysis were taken from markets located around Yogyakarta. Experiment was conducted by using 25 broilers as experimental animals. Total of 512 broiler samples for field research, were taken by using double-stage method from different locations at the district of Kabupaten Sleman. Results of this research showed that deltamethrin analysis procedure using HPLC was optimal and had good validity. Analysis procedure has been qualified for the main parameter validations. The validity analysis was supported by the analysis result of Kappa suitability with good categories (Kappa = 0,68). Oral exposure of deltamethrin through drinking water showed that there was correlation between deltamethrin treatment and residue in the blood, liver, and meat. The prevalence of deltamethrin residue was 17,6% with the mean of positive samples that contained deltamethrin 0,709 mg/kg. The Factors associated with increase the likelihood of positive samples of meat residue were animal health management (OR = 191,066), types of farm bedding (OR = 14,912), lacking of business experience(OR = 11,361), farms in the southeast region (OR = 11,269), the usage of ground water (OR = 10,351), unideally disinfection program of warehouses (OR = 6,092), limitation access to the farm (OR = 5,840), and presence of deltamethrin in the water (OR = 2,098). The Factors associated with decrease the likelihood of positive samples of meat residue were the location of farms in the northeast region (OR = 0,007), the sanitation program incoming vehicles (OR = 0,121), proportional arrangement of workers number (OR = 0,126), controlling farm�s environment (OR = 0,146), the presence of deltamethrin in the liver (OR = 0,202), open system of water installation (OR = 0,226), chicken�s population in the farm > 10.000 (OR = 0,364), postal type of broiler�s house (OR = 0,455), veterinarian as farm�s manager (OR = 0,485). Factors that associated and increased meat residue�s level were vehicle disinfection program (coefficient = 0,439), flexibility of working arrangements (coefficient = 0,261), presence of deltamethrin in the water from Pesticide residue in the meat and liver of broiler causes troubles for consumers in getting safe, healthy, whole, and halal nutrients. This research was aimed to carry out an optimization and validation of deltamethrin analysis procedure by using high performance liquid chromatography (HPLC), based on specification of parameter, precision, accuracy, limit of quantification, linearity, and confirmation of the compliance level by using Kappa test. The other aim of this research was to carry out the pharmacology experiment on deltamethrin residue in the meat of broiler that had been fed with different dosages of deltamethrin orally and analyzed its correlation between treatment and concentration found in the specimens. Research on prevalence and situation description of deltamethrin residue in meat of broiler at the district of Kabupaten Sleman, including the the possible associated factors, was carried out by using epidemiology study. The main equipment used for the residue analysis in tissue was HPLC with the appropriate procedure. The research consisted of the stage of validation and suitability analysis, experimental stage, and field research. Samples that were used for validation analysis were taken from markets located around Yogyakarta. Experiment was conducted by using 25 broilers as experimental animals. Total of 512 broiler samples for field research, were taken by using double-stage method from different locations at the district of Kabupaten Sleman. Results of this research showed that deltamethrin analysis procedure using HPLC was optimal and had good validity. Analysis procedure has been qualified for the main parameter validations. The validity analysis was supported by the analysis result of Kappa suitability with good categories (Kappa = 0,68). Oral exposure of deltamethrin through drinking water showed that there was correlation between deltamethrin treatment and residue in the blood, liver, and meat. The prevalence of deltamethrin residue was 17,6% with the mean of positive samples that contained deltamethrin 0,709 mg/kg. The Factors associated with increase the likelihood of positive samples of meat residue were animal health management (OR = 191,066), types of farm bedding (OR = 14,912), lacking of business experience(OR = 11,361), farms in the southeast region (OR = 11,269), the usage of ground water (OR = 10,351), unideally disinfection program of warehouses (OR = 6,092), limitation access to the farm (OR = 5,840), and presence of deltamethrin in the water (OR = 2,098). The Factors associated with decrease the likelihood of positive samples of meat residue were the location of farms in the northeast region (OR = 0,007), the sanitation program incoming vehicles (OR = 0,121), proportional arrangement of workers number (OR = 0,126), controlling farm�s environment (OR = 0,146), the presence of deltamethrin in the liver (OR = 0,202), open system of water installation (OR = 0,226), chicken�s population in the farm > 10.000 (OR = 0,364), postal type of broiler�s house (OR = 0,455), veterinarian as farm�s manager (OR = 0,485). Factors that associated and increased meat residue�s level were vehicle disinfection program (coefficient = 0,439), flexibility of working arrangements (coefficient = 0,261), presence of deltamethrin in the water from Pesticide residue in the meat and liver of broiler causes troubles for consumers in getting safe, healthy, whole, and halal nutrients. This research was aimed to carry out an optimization and validation of deltamethrin analysis procedure by using high performance liquid chromatography (HPLC), based on specification of parameter, precision, accuracy, limit of quantification, linearity, and confirmation of the compliance level by using Kappa test. The other aim of this research was to carry out the pharmacology experiment on deltamethrin residue in the meat of broiler that had been fed with different dosages of deltamethrin orally and analyzed its correlation between treatment and concentration found in the specimens. Research on prevalence and situation description of deltamethrin residue in meat of broiler at the district of Kabupaten Sleman, including the the possible associated factors, was carried out by using epidemiology study. The main equipment used for the residue analysis in tissue was HPLC with the appropriate procedure. The research consisted of the stage of validation and suitability analysis, experimental stage, and field research. Samples that were used for validation analysis were taken from markets located around Yogyakarta. Experiment was conducted by using 25 broilers as experimental animals. Total of 512 broiler samples for field research, were taken by using double-stage method from different locations at the district of Kabupaten Sleman. Results of this research showed that deltamethrin analysis procedure using HPLC was optimal and had good validity. Analysis procedure has been qualified for the main parameter validations. The validity analysis was supported by the analysis result of Kappa suitability with good categories (Kappa = 0,68). Oral exposure of deltamethrin through drinking water showed that there was correlation between deltamethrin treatment and residue in the blood, liver, and meat. The prevalence of deltamethrin residue was 17,6% with the mean of positive samples that contained deltamethrin 0,709 mg/kg. The Factors associated with increase the likelihood of positive samples of meat residue were animal health management (OR = 191,066), types of farm bedding (OR = 14,912), lacking of business experience(OR = 11,361), farms in the southeast region (OR = 11,269), the usage of ground water (OR = 10,351), unideally disinfection program of warehouses (OR = 6,092), limitation access to the farm (OR = 5,840), and presence of deltamethrin in the water (OR = 2,098). The Factors associated with decrease the likelihood of positive samples of meat residue were the location of farms in the northeast region (OR = 0,007), the sanitation program incoming vehicles (OR = 0,121), proportional arrangement of workers number (OR = 0,126), controlling farm�s environment (OR = 0,146), the presence of deltamethrin in the liver (OR = 0,202), open system of water installation (OR = 0,226), chicken�s population in the farm > 10.000 (OR = 0,364), postal type of broiler�s house (OR = 0,455), veterinarian as farm�s manager (OR = 0,485). Factors that associated and increased meat residue�s level were vehicle disinfection program (coefficient = 0,439), flexibility of working arrangements (coefficient = 0,261), presence of deltamethrin in the water from Pesticide residue in the meat and liver of broiler causes troubles for consumers in getting safe, healthy, whole, and halal nutrients. This research was aimed to carry out an optimization and validation of deltamethrin analysis procedure by using high performance liquid chromatography (HPLC), based on specification of parameter, precision, accuracy, limit of quantification, linearity, and confirmation of the compliance level by using Kappa test. The other aim of this research was to carry out the pharmacology experiment on deltamethrin residue in the meat of broiler that had been fed with different dosages of deltamethrin orally and analyzed its correlation between treatment and concentration found in the specimens. Research on prevalence and situation description of deltamethrin residue in meat of broiler at the district of Kabupaten Sleman, including the the possible associated factors, was carried out by using epidemiology study. The main equipment used for the residue analysis in tissue was HPLC with the appropriate procedure. The research consisted of the stage of validation and suitability analysis, experimental stage, and field research. Samples that were used for validation analysis were taken from markets located around Yogyakarta. Experiment was conducted by using 25 broilers as experimental animals. Total of 512 broiler samples for field research, were taken by using double-stage method from different locations at the district of Kabupaten Sleman. Results of this research showed that deltamethrin analysis procedure using HPLC was optimal and had good validity. Analysis procedure has been qualified for the main parameter validations. The validity analysis was supported by the analysis result of Kappa suitability with good categories (Kappa = 0,68). Oral exposure of deltamethrin through drinking water showed that there was correlation between deltamethrin treatment and residue in the blood, liver, and meat. The prevalence of deltamethrin residue was 17,6% with the mean of positive samples that contained deltamethrin 0,709 mg/kg. The Factors associated with increase the likelihood of positive samples of meat residue were animal health management (OR = 191,066), types of farm bedding (OR = 14,912), lacking of business experience(OR = 11,361), farms in the southeast region (OR = 11,269), the usage of ground water (OR = 10,351), unideally disinfection program of warehouses (OR = 6,092), limitation access to the farm (OR = 5,840), and presence of deltamethrin in the water (OR = 2,098). The Factors associated with decrease the likelihood of positive samples of meat residue were the location of farms in the northeast region (OR = 0,007), the sanitation program incoming vehicles (OR = 0,121), proportional arrangement of workers number (OR = 0,126), controlling farm�s environment (OR = 0,146), the presence of deltamethrin in the liver (OR = 0,202), open system of water installation (OR = 0,226), chicken�s population in the farm > 10.000 (OR = 0,364), postal type of broiler�s house (OR = 0,455), veterinarian as farm�s manager (OR = 0,485). Factors that associated and increased meat residue�s level were vehicle disinfection program (coefficient = 0,439), flexibility of working arrangements (coefficient = 0,261), presence of deltamethrin in the water from Pesticide residue in the meat and liver of broiler causes troubles for consumers in getting safe, healthy, whole, and halal nutrients. This research was aimed to carry out an optimization and validation of deltamethrin analysis procedure by using high performance liquid chromatography (HPLC), based on specification of parameter, precision, accuracy, limit of quantification, linearity, and confirmation of the compliance level by using Kappa test. The other aim of this research was to carry out the pharmacology experiment on deltamethrin residue in the meat of broiler that had been fed with different dosages of deltamethrin orally and analyzed its correlation between treatment and concentration found in the specimens. Research on prevalence and situation description of deltamethrin residue in meat of broiler at the district of Kabupaten Sleman, including the the possible associated factors, was carried out by using epidemiology study. The main equipment used for the residue analysis in tissue was HPLC with the appropriate procedure. The research consisted of the stage of validation and suitability analysis, experimental stage, and field research. Samples that were used for validation analysis were taken from markets located around Yogyakarta. Experiment was conducted by using 25 broilers as experimental animals. Total of 512 broiler samples for field research, were taken by using double-stage method from different locations at the district of Kabupaten Sleman. Results of this research showed that deltamethrin analysis procedure using HPLC was optimal and had good validity. Analysis procedure has been qualified for the main parameter validations. The validity analysis was supported by the analysis result of Kappa suitability with good categories (Kappa = 0,68). Oral exposure of deltamethrin through drinking water showed that there was correlation between deltamethrin treatment and residue in the blood, liver, and meat. The prevalence of deltamethrin residue was 17,6% with the mean of positive samples that contained deltamethrin 0,709 mg/kg. The Factors associated with increase the likelihood of positive samples of meat residue were animal health management (OR = 191,066), types of farm bedding (OR = 14,912), lacking of business experience(OR = 11,361), farms in the southeast region (OR = 11,269), the usage of ground water (OR = 10,351), unideally disinfection program of warehouses (OR = 6,092), limitation access to the farm (OR = 5,840), and presence of deltamethrin in the water (OR = 2,098). The Factors associated with decrease the likelihood of positive samples of meat residue were the location of farms in the northeast region (OR = 0,007), the sanitation program incoming vehicles (OR = 0,121), proportional arrangement of workers number (OR = 0,126), controlling farm�s environment (OR = 0,146), the presence of deltamethrin in the liver (OR = 0,202), open system of water installation (OR = 0,226), chicken�s population in the farm > 10.000 (OR = 0,364), postal type of broiler�s house (OR = 0,455), veterinarian as farm�s manager (OR = 0,485). Factors that associated and increased meat residue�s level were vehicle disinfection program (coefficient = 0,439), flexibility of working arrangements (coefficient = 0,261), presence of deltamethrin in the water from Pesticide residue in the meat and liver of broiler causes troubles for consumers in getting safe, healthy, whole, and halal nutrients. This research was aimed to carry out an optimization and validation of deltamethrin analysis procedure by using high performance liquid chromatography (HPLC), based on specification of parameter, precision, accuracy, limit of quantification, linearity, and confirmation of the compliance level by using Kappa test. The other aim of this research was to carry out the pharmacology experiment on deltamethrin residue in the meat of broiler that had been fed with different dosages of deltamethrin orally and analyzed its correlation between treatment and concentration found in the specimens. Research on prevalence and situation description of deltamethrin residue in meat of broiler at the district of Kabupaten Sleman, including the the possible associated factors, was carried out by using epidemiology study. The main equipment used for the residue analysis in tissue was HPLC with the appropriate procedure. The research consisted of the stage of validation and suitability analysis, experimental stage, and field research. Samples that were used for validation analysis were taken from markets located around Yogyakarta. Experiment was conducted by using 25 broilers as experimental animals. Total of 512 broiler samples for field research, were taken by using double-stage method from different locations at the district of Kabupaten Sleman. Results of this research showed that deltamethrin analysis procedure using HPLC was optimal and had good validity. Analysis procedure has been qualified for the main parameter validations. The validity analysis was supported by the analysis result of Kappa suitability with good categories (Kappa = 0,68). Oral exposure of deltamethrin through drinking water showed that there was correlation between deltamethrin treatment and residue in the blood, liver, and meat. The prevalence of deltamethrin residue was 17,6% with the mean of positive samples that contained deltamethrin 0,709 mg/kg. The Factors associated with increase the likelihood of positive samples of meat residue were animal health management (OR = 191,066), types of farm bedding (OR = 14,912), lacking of business experience(OR = 11,361), farms in the southeast region (OR = 11,269), the usage of ground water (OR = 10,351), unideally disinfection program of warehouses (OR = 6,092), limitation access to the farm (OR = 5,840), and presence of deltamethrin in the water (OR = 2,098). The Factors associated with decrease the likelihood of positive samples of meat residue were the location of farms in the northeast region (OR = 0,007), the sanitation program incoming vehicles (OR = 0,121), proportional arrangement of workers number (OR = 0,126), controlling farm�s environment (OR = 0,146), the presence of deltamethrin in the liver (OR = 0,202), open system of water installation (OR = 0,226), chicken�s population in the farm > 10.000 (OR = 0,364), postal type of broiler�s house (OR = 0,455), veterinarian as farm�s manager (OR = 0,485). Factors that associated and increased meat residue�s level were vehicle disinfection program (coefficient = 0,439), flexibility of working arrangements (coefficient = 0,261), presence of deltamethrin in the water from the environment (coefficient = 0,223), chicken�s population in the farm > 10.000 (coefficient = 0,208). Factors that were associated and decrease meat residue�s level were restriction of access (coefficient = -0,629), main job of workers (coefficient = -0,316), Veterinarian or engineers of as farm�s manager (coefficient = -0,274), and chicken period < 35 days (coefficient = -0,242). The research concluded that HPLC procedure was valid to analyze deltametrin. Deltametrin residue in boiler�s meat was caused by external factors. The prevalence of broiler meat residue on Sleman was 17,6%, contained deltamethrin 0,709 mg/kg in average, and influence by farm management and environmental factors. [Yogyakarta] : Universitas Gadjah Mada 2014 Thesis NonPeerReviewed , R. Gagak Donny Satria and , Prof. Dr. drh. Bambang Sumiarto, S.U., M.Sc. (2014) ANALISIS FARMAKOLOGI DAN EPIDEMIOLOGI RESIDU DELTAMETRIN PADA DAGING BROILER DI WILAYAH KABUPATEN SLEMAN DAERAH ISTIMEWA YOGYAKARTA. UNSPECIFIED thesis, UNSPECIFIED. http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=71161 |
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ETD , R. Gagak Donny Satria , Prof. Dr. drh. Bambang Sumiarto, S.U., M.Sc. ANALISIS FARMAKOLOGI DAN EPIDEMIOLOGI RESIDU DELTAMETRIN PADA DAGING BROILER DI WILAYAH KABUPATEN SLEMAN DAERAH ISTIMEWA YOGYAKARTA |
format |
Theses and Dissertations NonPeerReviewed |
author |
, R. Gagak Donny Satria , Prof. Dr. drh. Bambang Sumiarto, S.U., M.Sc. |
author_facet |
, R. Gagak Donny Satria , Prof. Dr. drh. Bambang Sumiarto, S.U., M.Sc. |
author_sort |
, R. Gagak Donny Satria |
title |
ANALISIS FARMAKOLOGI DAN EPIDEMIOLOGI RESIDU DELTAMETRIN PADA DAGING BROILER DI WILAYAH KABUPATEN SLEMAN DAERAH ISTIMEWA YOGYAKARTA |
title_short |
ANALISIS FARMAKOLOGI DAN EPIDEMIOLOGI RESIDU DELTAMETRIN PADA DAGING BROILER DI WILAYAH KABUPATEN SLEMAN DAERAH ISTIMEWA YOGYAKARTA |
title_full |
ANALISIS FARMAKOLOGI DAN EPIDEMIOLOGI RESIDU DELTAMETRIN PADA DAGING BROILER DI WILAYAH KABUPATEN SLEMAN DAERAH ISTIMEWA YOGYAKARTA |
title_fullStr |
ANALISIS FARMAKOLOGI DAN EPIDEMIOLOGI RESIDU DELTAMETRIN PADA DAGING BROILER DI WILAYAH KABUPATEN SLEMAN DAERAH ISTIMEWA YOGYAKARTA |
title_full_unstemmed |
ANALISIS FARMAKOLOGI DAN EPIDEMIOLOGI RESIDU DELTAMETRIN PADA DAGING BROILER DI WILAYAH KABUPATEN SLEMAN DAERAH ISTIMEWA YOGYAKARTA |
title_sort |
analisis farmakologi dan epidemiologi residu deltametrin pada daging broiler di wilayah kabupaten sleman daerah istimewa yogyakarta |
publisher |
[Yogyakarta] : Universitas Gadjah Mada |
publishDate |
2014 |
url |
https://repository.ugm.ac.id/130732/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=71161 |
_version_ |
1681233201160257536 |
description |
Pesticide residue in the meat and liver of broiler causes troubles for
consumers in getting safe, healthy, whole, and halal nutrients. This research was
aimed to carry out an optimization and validation of deltamethrin analysis
procedure by using high performance liquid chromatography (HPLC), based on
specification of parameter, precision, accuracy, limit of quantification, linearity,
and confirmation of the compliance level by using Kappa test. The other aim of
this research was to carry out the pharmacology experiment on deltamethrin
residue in the meat of broiler that had been fed with different dosages of
deltamethrin orally and analyzed its correlation between treatment and
concentration found in the specimens. Research on prevalence and situation
description of deltamethrin residue in meat of broiler at the district of Kabupaten
Sleman, including the the possible associated factors, was carried out by using
epidemiology study. The main equipment used for the residue analysis in tissue
was HPLC with the appropriate procedure. The research consisted of the stage of
validation and suitability analysis, experimental stage, and field research.
Samples that were used for validation analysis were taken from markets located
around Yogyakarta. Experiment was conducted by using 25 broilers as
experimental animals. Total of 512 broiler samples for field research, were taken
by using double-stage method from different locations at the district of Kabupaten
Sleman. Results of this research showed that deltamethrin analysis procedure
using HPLC was optimal and had good validity. Analysis procedure has been
qualified for the main parameter validations. The validity analysis was supported
by the analysis result of Kappa suitability with good categories (Kappa = 0,68).
Oral exposure of deltamethrin through drinking water showed that there was
correlation between deltamethrin treatment and residue in the blood, liver, and
meat. The prevalence of deltamethrin residue was 17,6% with the mean of positive
samples that contained deltamethrin 0,709 mg/kg. The Factors associated with
increase the likelihood of positive samples of meat residue were animal health
management (OR = 191,066), types of farm bedding (OR = 14,912), lacking of
business experience(OR = 11,361), farms in the southeast region (OR = 11,269),
the usage of ground water (OR = 10,351), unideally disinfection program of
warehouses (OR = 6,092), limitation access to the farm (OR = 5,840), and
presence of deltamethrin in the water (OR = 2,098). The Factors associated with
decrease the likelihood of positive samples of meat residue were the location of
farms in the northeast region (OR = 0,007), the sanitation program incoming
vehicles (OR = 0,121), proportional arrangement of workers number
(OR = 0,126), controlling farm�s environment (OR = 0,146), the presence of
deltamethrin in the liver (OR = 0,202), open system of water installation
(OR = 0,226), chicken�s population in the farm > 10.000 (OR = 0,364), postal
type of broiler�s house (OR = 0,455), veterinarian as farm�s manager
(OR = 0,485). Factors that associated and increased meat residue�s level were
vehicle disinfection program (coefficient = 0,439), flexibility of working
arrangements (coefficient = 0,261), presence of deltamethrin in the water from Pesticide residue in the meat and liver of broiler causes troubles for
consumers in getting safe, healthy, whole, and halal nutrients. This research was
aimed to carry out an optimization and validation of deltamethrin analysis
procedure by using high performance liquid chromatography (HPLC), based on
specification of parameter, precision, accuracy, limit of quantification, linearity,
and confirmation of the compliance level by using Kappa test. The other aim of
this research was to carry out the pharmacology experiment on deltamethrin
residue in the meat of broiler that had been fed with different dosages of
deltamethrin orally and analyzed its correlation between treatment and
concentration found in the specimens. Research on prevalence and situation
description of deltamethrin residue in meat of broiler at the district of Kabupaten
Sleman, including the the possible associated factors, was carried out by using
epidemiology study. The main equipment used for the residue analysis in tissue
was HPLC with the appropriate procedure. The research consisted of the stage of
validation and suitability analysis, experimental stage, and field research.
Samples that were used for validation analysis were taken from markets located
around Yogyakarta. Experiment was conducted by using 25 broilers as
experimental animals. Total of 512 broiler samples for field research, were taken
by using double-stage method from different locations at the district of Kabupaten
Sleman. Results of this research showed that deltamethrin analysis procedure
using HPLC was optimal and had good validity. Analysis procedure has been
qualified for the main parameter validations. The validity analysis was supported
by the analysis result of Kappa suitability with good categories (Kappa = 0,68).
Oral exposure of deltamethrin through drinking water showed that there was
correlation between deltamethrin treatment and residue in the blood, liver, and
meat. The prevalence of deltamethrin residue was 17,6% with the mean of positive
samples that contained deltamethrin 0,709 mg/kg. The Factors associated with
increase the likelihood of positive samples of meat residue were animal health
management (OR = 191,066), types of farm bedding (OR = 14,912), lacking of
business experience(OR = 11,361), farms in the southeast region (OR = 11,269),
the usage of ground water (OR = 10,351), unideally disinfection program of
warehouses (OR = 6,092), limitation access to the farm (OR = 5,840), and
presence of deltamethrin in the water (OR = 2,098). The Factors associated with
decrease the likelihood of positive samples of meat residue were the location of
farms in the northeast region (OR = 0,007), the sanitation program incoming
vehicles (OR = 0,121), proportional arrangement of workers number
(OR = 0,126), controlling farm�s environment (OR = 0,146), the presence of
deltamethrin in the liver (OR = 0,202), open system of water installation
(OR = 0,226), chicken�s population in the farm > 10.000 (OR = 0,364), postal
type of broiler�s house (OR = 0,455), veterinarian as farm�s manager
(OR = 0,485). Factors that associated and increased meat residue�s level were
vehicle disinfection program (coefficient = 0,439), flexibility of working
arrangements (coefficient = 0,261), presence of deltamethrin in the water from Pesticide residue in the meat and liver of broiler causes troubles for
consumers in getting safe, healthy, whole, and halal nutrients. This research was
aimed to carry out an optimization and validation of deltamethrin analysis
procedure by using high performance liquid chromatography (HPLC), based on
specification of parameter, precision, accuracy, limit of quantification, linearity,
and confirmation of the compliance level by using Kappa test. The other aim of
this research was to carry out the pharmacology experiment on deltamethrin
residue in the meat of broiler that had been fed with different dosages of
deltamethrin orally and analyzed its correlation between treatment and
concentration found in the specimens. Research on prevalence and situation
description of deltamethrin residue in meat of broiler at the district of Kabupaten
Sleman, including the the possible associated factors, was carried out by using
epidemiology study. The main equipment used for the residue analysis in tissue
was HPLC with the appropriate procedure. The research consisted of the stage of
validation and suitability analysis, experimental stage, and field research.
Samples that were used for validation analysis were taken from markets located
around Yogyakarta. Experiment was conducted by using 25 broilers as
experimental animals. Total of 512 broiler samples for field research, were taken
by using double-stage method from different locations at the district of Kabupaten
Sleman. Results of this research showed that deltamethrin analysis procedure
using HPLC was optimal and had good validity. Analysis procedure has been
qualified for the main parameter validations. The validity analysis was supported
by the analysis result of Kappa suitability with good categories (Kappa = 0,68).
Oral exposure of deltamethrin through drinking water showed that there was
correlation between deltamethrin treatment and residue in the blood, liver, and
meat. The prevalence of deltamethrin residue was 17,6% with the mean of positive
samples that contained deltamethrin 0,709 mg/kg. The Factors associated with
increase the likelihood of positive samples of meat residue were animal health
management (OR = 191,066), types of farm bedding (OR = 14,912), lacking of
business experience(OR = 11,361), farms in the southeast region (OR = 11,269),
the usage of ground water (OR = 10,351), unideally disinfection program of
warehouses (OR = 6,092), limitation access to the farm (OR = 5,840), and
presence of deltamethrin in the water (OR = 2,098). The Factors associated with
decrease the likelihood of positive samples of meat residue were the location of
farms in the northeast region (OR = 0,007), the sanitation program incoming
vehicles (OR = 0,121), proportional arrangement of workers number
(OR = 0,126), controlling farm�s environment (OR = 0,146), the presence of
deltamethrin in the liver (OR = 0,202), open system of water installation
(OR = 0,226), chicken�s population in the farm > 10.000 (OR = 0,364), postal
type of broiler�s house (OR = 0,455), veterinarian as farm�s manager
(OR = 0,485). Factors that associated and increased meat residue�s level were
vehicle disinfection program (coefficient = 0,439), flexibility of working
arrangements (coefficient = 0,261), presence of deltamethrin in the water from Pesticide residue in the meat and liver of broiler causes troubles for
consumers in getting safe, healthy, whole, and halal nutrients. This research was
aimed to carry out an optimization and validation of deltamethrin analysis
procedure by using high performance liquid chromatography (HPLC), based on
specification of parameter, precision, accuracy, limit of quantification, linearity,
and confirmation of the compliance level by using Kappa test. The other aim of
this research was to carry out the pharmacology experiment on deltamethrin
residue in the meat of broiler that had been fed with different dosages of
deltamethrin orally and analyzed its correlation between treatment and
concentration found in the specimens. Research on prevalence and situation
description of deltamethrin residue in meat of broiler at the district of Kabupaten
Sleman, including the the possible associated factors, was carried out by using
epidemiology study. The main equipment used for the residue analysis in tissue
was HPLC with the appropriate procedure. The research consisted of the stage of
validation and suitability analysis, experimental stage, and field research.
Samples that were used for validation analysis were taken from markets located
around Yogyakarta. Experiment was conducted by using 25 broilers as
experimental animals. Total of 512 broiler samples for field research, were taken
by using double-stage method from different locations at the district of Kabupaten
Sleman. Results of this research showed that deltamethrin analysis procedure
using HPLC was optimal and had good validity. Analysis procedure has been
qualified for the main parameter validations. The validity analysis was supported
by the analysis result of Kappa suitability with good categories (Kappa = 0,68).
Oral exposure of deltamethrin through drinking water showed that there was
correlation between deltamethrin treatment and residue in the blood, liver, and
meat. The prevalence of deltamethrin residue was 17,6% with the mean of positive
samples that contained deltamethrin 0,709 mg/kg. The Factors associated with
increase the likelihood of positive samples of meat residue were animal health
management (OR = 191,066), types of farm bedding (OR = 14,912), lacking of
business experience(OR = 11,361), farms in the southeast region (OR = 11,269),
the usage of ground water (OR = 10,351), unideally disinfection program of
warehouses (OR = 6,092), limitation access to the farm (OR = 5,840), and
presence of deltamethrin in the water (OR = 2,098). The Factors associated with
decrease the likelihood of positive samples of meat residue were the location of
farms in the northeast region (OR = 0,007), the sanitation program incoming
vehicles (OR = 0,121), proportional arrangement of workers number
(OR = 0,126), controlling farm�s environment (OR = 0,146), the presence of
deltamethrin in the liver (OR = 0,202), open system of water installation
(OR = 0,226), chicken�s population in the farm > 10.000 (OR = 0,364), postal
type of broiler�s house (OR = 0,455), veterinarian as farm�s manager
(OR = 0,485). Factors that associated and increased meat residue�s level were
vehicle disinfection program (coefficient = 0,439), flexibility of working
arrangements (coefficient = 0,261), presence of deltamethrin in the water from Pesticide residue in the meat and liver of broiler causes troubles for
consumers in getting safe, healthy, whole, and halal nutrients. This research was
aimed to carry out an optimization and validation of deltamethrin analysis
procedure by using high performance liquid chromatography (HPLC), based on
specification of parameter, precision, accuracy, limit of quantification, linearity,
and confirmation of the compliance level by using Kappa test. The other aim of
this research was to carry out the pharmacology experiment on deltamethrin
residue in the meat of broiler that had been fed with different dosages of
deltamethrin orally and analyzed its correlation between treatment and
concentration found in the specimens. Research on prevalence and situation
description of deltamethrin residue in meat of broiler at the district of Kabupaten
Sleman, including the the possible associated factors, was carried out by using
epidemiology study. The main equipment used for the residue analysis in tissue
was HPLC with the appropriate procedure. The research consisted of the stage of
validation and suitability analysis, experimental stage, and field research.
Samples that were used for validation analysis were taken from markets located
around Yogyakarta. Experiment was conducted by using 25 broilers as
experimental animals. Total of 512 broiler samples for field research, were taken
by using double-stage method from different locations at the district of Kabupaten
Sleman. Results of this research showed that deltamethrin analysis procedure
using HPLC was optimal and had good validity. Analysis procedure has been
qualified for the main parameter validations. The validity analysis was supported
by the analysis result of Kappa suitability with good categories (Kappa = 0,68).
Oral exposure of deltamethrin through drinking water showed that there was
correlation between deltamethrin treatment and residue in the blood, liver, and
meat. The prevalence of deltamethrin residue was 17,6% with the mean of positive
samples that contained deltamethrin 0,709 mg/kg. The Factors associated with
increase the likelihood of positive samples of meat residue were animal health
management (OR = 191,066), types of farm bedding (OR = 14,912), lacking of
business experience(OR = 11,361), farms in the southeast region (OR = 11,269),
the usage of ground water (OR = 10,351), unideally disinfection program of
warehouses (OR = 6,092), limitation access to the farm (OR = 5,840), and
presence of deltamethrin in the water (OR = 2,098). The Factors associated with
decrease the likelihood of positive samples of meat residue were the location of
farms in the northeast region (OR = 0,007), the sanitation program incoming
vehicles (OR = 0,121), proportional arrangement of workers number
(OR = 0,126), controlling farm�s environment (OR = 0,146), the presence of
deltamethrin in the liver (OR = 0,202), open system of water installation
(OR = 0,226), chicken�s population in the farm > 10.000 (OR = 0,364), postal
type of broiler�s house (OR = 0,455), veterinarian as farm�s manager
(OR = 0,485). Factors that associated and increased meat residue�s level were
vehicle disinfection program (coefficient = 0,439), flexibility of working
arrangements (coefficient = 0,261), presence of deltamethrin in the water from Pesticide residue in the meat and liver of broiler causes troubles for
consumers in getting safe, healthy, whole, and halal nutrients. This research was
aimed to carry out an optimization and validation of deltamethrin analysis
procedure by using high performance liquid chromatography (HPLC), based on
specification of parameter, precision, accuracy, limit of quantification, linearity,
and confirmation of the compliance level by using Kappa test. The other aim of
this research was to carry out the pharmacology experiment on deltamethrin
residue in the meat of broiler that had been fed with different dosages of
deltamethrin orally and analyzed its correlation between treatment and
concentration found in the specimens. Research on prevalence and situation
description of deltamethrin residue in meat of broiler at the district of Kabupaten
Sleman, including the the possible associated factors, was carried out by using
epidemiology study. The main equipment used for the residue analysis in tissue
was HPLC with the appropriate procedure. The research consisted of the stage of
validation and suitability analysis, experimental stage, and field research.
Samples that were used for validation analysis were taken from markets located
around Yogyakarta. Experiment was conducted by using 25 broilers as
experimental animals. Total of 512 broiler samples for field research, were taken
by using double-stage method from different locations at the district of Kabupaten
Sleman. Results of this research showed that deltamethrin analysis procedure
using HPLC was optimal and had good validity. Analysis procedure has been
qualified for the main parameter validations. The validity analysis was supported
by the analysis result of Kappa suitability with good categories (Kappa = 0,68).
Oral exposure of deltamethrin through drinking water showed that there was
correlation between deltamethrin treatment and residue in the blood, liver, and
meat. The prevalence of deltamethrin residue was 17,6% with the mean of positive
samples that contained deltamethrin 0,709 mg/kg. The Factors associated with
increase the likelihood of positive samples of meat residue were animal health
management (OR = 191,066), types of farm bedding (OR = 14,912), lacking of
business experience(OR = 11,361), farms in the southeast region (OR = 11,269),
the usage of ground water (OR = 10,351), unideally disinfection program of
warehouses (OR = 6,092), limitation access to the farm (OR = 5,840), and
presence of deltamethrin in the water (OR = 2,098). The Factors associated with
decrease the likelihood of positive samples of meat residue were the location of
farms in the northeast region (OR = 0,007), the sanitation program incoming
vehicles (OR = 0,121), proportional arrangement of workers number
(OR = 0,126), controlling farm�s environment (OR = 0,146), the presence of
deltamethrin in the liver (OR = 0,202), open system of water installation
(OR = 0,226), chicken�s population in the farm > 10.000 (OR = 0,364), postal
type of broiler�s house (OR = 0,455), veterinarian as farm�s manager
(OR = 0,485). Factors that associated and increased meat residue�s level were
vehicle disinfection program (coefficient = 0,439), flexibility of working
arrangements (coefficient = 0,261), presence of deltamethrin in the water from the environment (coefficient = 0,223), chicken�s population in the farm > 10.000
(coefficient = 0,208). Factors that were associated and decrease meat residue�s
level were restriction of access (coefficient = -0,629), main job of workers
(coefficient = -0,316), Veterinarian or engineers of as farm�s manager
(coefficient = -0,274), and chicken period < 35 days (coefficient = -0,242). The
research concluded that HPLC procedure was valid to analyze deltametrin.
Deltametrin residue in boiler�s meat was caused by external factors. The
prevalence of broiler meat residue on Sleman was 17,6%, contained deltamethrin
0,709 mg/kg in average, and influence by farm management and environmental
factors. |