HUBUNGAN ANTARA WAKTU PAPARAN CHLORINE DIOXIDE GELDANZONA HAMBAT PERTUMBUHAN BAKTERIPorphyromonas gingivalis PENYEBAB PENYAKIT PERIODONTAL

• Main Authors: , STELLA ADVENA ANINDITA, , Dr. drg. Ahmad Syaify, Sp.Perio (K)
• Format: Theses and Dissertations NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2014
• Subjects: ETD
• Online Access: https://repository.ugm.ac.id/131660/; http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=72158
• Institution: Universitas Gadjah Mada

The purpose of this study was to determine the relationship between time of exposureto Chlorine dioxide geland inhibitory zones of growth of Porphyromonasgingivalis bacteria as the cause of periodontal disease. The method that used in this study was agar diffusion tests with MHA (Mueller Hinton Agar) platewhich had swabbed with Porphyromonasgingivalis. Six wells (diameter 6 mm) were made in plate then 4 wells dropped with Chlorine dioxide gel (50µl), 2 wells dropped with Chlorhexidinedigluconate 0,12 % gel (50µl) and Aquades sterile (50µl). The plate were incubated for 48 hours and observed periodically at 12, 18, 24, and 48 hours at the temperature of 37 o C. The relationship between time of exposureto Chlorine dioxide geland inhibitory zones of growth of Porphyromonasgingivaliscan be determined by measuring the diameter of inhibitory zone using sliding calipers in scale of 0,02 mm. Statistical analysis was carried out using a Spearmen correlation test. The results of the analysis with Spearman correlation test was obtained at -0,856 coefficient correlation with p=0,000 (p<0,01) showed a significant association with negative direction, that an increase of time exposure followed by a decrease in bacterial zones inhibition. Bonferronitest resultsis0,037(p <0.05), showeda significant reduction inbacterialzonesinhibitionatthe observation timeof12hoursto 48hours.It can be concluded that there is a significant association with negative directionbetween time of exposureto Chlorine dioxide geland inhibitory zones of growth of Porphyromonasgingivalis bacteria as the cause of periodontal disease.