STUDI PELEPASAN KURKUMIN MENGGUNAKAN MEMBRAN KITOSAN-PEKTIN DENGAN PENAMBAHAN ASAM LAURAT SEBAGAI EMULSIFIER
Curcumine release from chitosan-pectin film using lauric acid as emulsifier had been studied. The aim of this study was to determine the optimum condition of curcumin release using some variations, such as curcumine consentrations, lauric acid concentrations, ethanol concentrations and pH of solvent...
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| Main Authors: | , |
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| Format: | Theses and Dissertations NonPeerReviewed |
| Published: |
[Yogyakarta] : Universitas Gadjah Mada
2014
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| Online Access: | https://repository.ugm.ac.id/132645/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=73184 |
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| Institution: | Universitas Gadjah Mada |
| Summary: | Curcumine release from chitosan-pectin film using lauric acid as
emulsifier had been studied. The aim of this study was to determine the optimum
condition of curcumin release using some variations, such as curcumine
consentrations, lauric acid concentrations, ethanol concentrations and pH of
solvent. Film was prepared by mixing pectin with aquades, then adding chitosan
and acetic acid 1%, then adding lauric acid and curcumine until it was mixed
completely. The products were characterized by spectrometer IR. Curcumin
release had been done by immersing film in a phospate buffer-ethanol solution for
6 hours. The concentration of curcumine release was measured by
Spectrofotometer UV-Vis. Curcumine release kinetics were analyzed by zeroorder
model, first-order model, Higuchi model and Korsmeyer-Peppas model.
The ressult showed that the most suitable kinetics model of this
experiment was Korsmeyer-Peppas. The optimum condition of curcumin release
had been given by film which had 200ppm curcumin and 5mg lauric acid. The
most optimum solvent was phosphate buffer:ethanol 80:20 pH7. The release rate
was 0,31 cm-1. |
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