Profil Serum Amyloid A (SAA) pada Pasien Angina Pektoris Stabil di RSUP DR. Sardjito Yogyakarta

• Main Authors: , AVIAN KRISPRATAMA, , Dr. Setyawati, Sp.PK(K)
• Format: Theses and Dissertations NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2014
• Subjects: ETD
• Online Access: https://repository.ugm.ac.id/133217/; http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=73778
• Institution: Universitas Gadjah Mada

Background : Stable Angina Pectoris is a symptom that occur because of myocardial ischemia that caused by fat deposition on the wall of coronarian artery (atherosclerosis), when the progress still remains it can lead to myocardial infarction and furthermore death. Serum Amyloid A is one of the clinical chemical parameter as a sign of acute inflamation, that suspected play an important role on progression of atherosclerosis. In general, function of SAA as an specific laboratory marker can�t be precisely postulated, there are some things that remains unclear according to researches that contradictively one to another. Methods : The study design was a analytical descriptive study of patients with stable angina pectoris that received treatment in ICCU Hospital Dr . Sardjito . Examination of SAA was measured by sandwich ELISA method. Results : There were 26 patients with stable angina pectoris that joined this research. Analysis with Mann Whitney test come out with a result which says that there is no significant difference of SAA level between patient with risk factor of atherosclerosis and without risk factor. There is no significant correlation between SAA and other clinical chemical parameter that analyzed by Spearman test. Conclusions : There is a significant diference of SAA level on patient with diaberes as a risk factor of atherosclerosis. There is no significant correlation between SAA and other clinical chemical parameter.