OPTIMASI KOMPOSISI CAIRAN PENYARI EKSTRAK BENALU ALPUKAT (Scurrula atropurpurea (Bl.) Dans.) DENGAN PARAMETER RENDEMEN DAN KADAR FLAVONOID

• Main Authors: , Slamet Wahyono, Drs., , Prof. Dr.Suwidjiyo Pramono, DEA, Apt.
• Format: Theses and Dissertations NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2014
• Subjects: ETD
• Online Access: https://repository.ugm.ac.id/134239/; http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=75297
• Institution: Universitas Gadjah Mada

Traditional medicine is widely used by Indonesian people especialy for cancer, mistletoe (Scurrula atropurpurea (Bl.) Dans.) as the one of plants has been used for cancer threatment. Several compounds had been identified from mistletoe herbs. There are six fatty acid, two compounds of tannis, two compounds of xantin, one monoterpen glycoside, four compounds of flavans and two flavonol glycoside is quercitrin and rutin. The quality of natural product determine of extract as an active substance. In order to increase the quality of benalu extract was done using simplex lattice design with flavonoids as parameter of standardization. The water and ethanol mixture were used as solvent extraction, and the optimal solvent obtained was applied in the extraction procedure of Scurrula atropurpurea herb. The assay of total flavonoid was done by spectrophotometry by Chang et.al methode.Variation of extraction methods performed to obtain the best extraction, in addition also conducted an evaluation of the benalu preparation in the community is by making infusa. Solvent composition of ethanol 75% was selected, then used as a solvent in the extract preparation. Extraction methods with ethanol 75% as a solvent in accordance with Farmakope Herbal Indonesia methods obtained 23,89% yield extracts and 4,183% flavonoid content. Other methods is maceration for 8 hours resulted 21,72% yield and 5,040% flavonoids content. The infusion resulted in 18.67% yield extractsand the total flavonoids content is 1.519 percent.