Penelitian pendahuluan pengaruh daun manggis sebagai rodentisida nabati pada mencit mus musculus strain balepsi: Preliminary study of the effect of mangosteen leaves as

• Main Author: Perpustakaan UGM, i-lib
• Format: Article NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2000
• Subjects: Jurnal i-lib UGM
• Online Access: https://repository.ugm.ac.id/24847/; http://i-lib.ugm.ac.id/jurnal/download.php?dataId=7825
• Institution: Universitas Gadjah Mada

ABSTRACT Research has been conducted at Pest and Disease Laboratory, Research Institute for Spices and Medicinal Crops, Bogor, during 1997-1998. The objective was to evaluate the possibility of Mangosteen (Garcinia mangostana) leaves to be used as botanical rodenticide which is tested to reproduction ability of mice Mus musculus. Eight to ten weeks old mice with the average weight of 25 gram were obtained from Research Institute for Livestock, Ciawi. Research was arranged at randomized block design, 8 treatments and 4 replications. Data was analyzed by determining the average value and their standard deviation values. Observations were done to the weight of testis, weight of embryo, number of embryo, volume of extracts drank by mice and mice behavior during experiment. Result revealed that there was no indication that the leaves extract affected the weight of testis, but it affected the number and weight of embryo. There was indication that mangosteen leaves acted as antifertility on mice. Giving leaves extract increased the total volume of extract drink. There was no abnormality at the activity of mice during experiment, included sex activity, poisonous symptoms and others. Key words : mangosteen, Mus musculus, antifertility INTISARI Penelitian dilaksanakan di Laboratorium Hama dan Penyakit, Balai Penelitian Tanaman Rernpah dan Obat, Bogor, pada tahun 1997-1998. Penelitian bertujuan untuk melihat kemungkinan digunakannya daun manggis (Garcinia mangostana Linn.) sebagai bahan rodentisida nabati, dengan melihat pengaruhnya path daya reproduksi mencit Mus musculus. Mencit yang berumur 8-10 minggu dengan berat rata-rata 25 gram diperdeh dari Balai Penelitian Ternak Ciawi yang merupakan hasil perbanyakan di Laboratorium Ternak. Penelitian disusun dalam acak kelompok, 8 perlakuan dan 4 ulangan. Data diana]isis dengan menghitung nilai tengah serta nilai standar deviasinya. Pengamatan meliputi berat testis, berat embrio, jumlah embrio, banyak air yang diminum dan tingkah laku mencit selama percobaan. Hasil penelitian menunjukkan, tidak ada indikasi bahwa sari daun manggis dapat menurunkan berat testis, namun demikian terlihat indikasi bahwa claim manggis berpengaruh sebagai bahan antifertilitas dengan mempengaruhi jumlah dan berat embrio yang dihasilkan. Daun manggis meningkatkan jumlah air yang diminum. Daun manggis tidak mempengaruhi tingkah laku mencit ataupun menimbulkan gejala keracunan selama percobaan berlangsung. Kata kunci : manggis, Mus musculus, antifertilitas