Serum iron level after ingestion of repeated dose of iron shortly after and 2 hours after meal

• Main Author: Perpustakaan UGM, i-lib
• Format: Article NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2009
• Subjects: Jurnal i-lib UGM
• Online Access: https://repository.ugm.ac.id/27750/; http://i-lib.ugm.ac.id/jurnal/download.php?dataId=10813
• Institution: Universitas Gadjah Mada

Ema Kristin. Mohammad Hakimi, Sri Kadarsih Soejono, Lukman Hakim -Serum iron level after ingestion of repeated dose of iron shortly after and 2 hours after meal Background: The prevalence of iron deficiency anemia in pregnant women is estimated to be higher than nonpregnant women. Ironsupplementation program has been proven clinicallyto improvethe hemoglobin (Hb)level of pregnant women. The absorption of iron is affected by food, therefore iron has to be given 2 hours after meal. However, in practice, iron was given shortly after meal. The physiologicalchange in pregnant women affects drug absorption, distribution, and eliminationphases. Objective: To understand serum iron level after ingestion of repeated dose of iron shortly after and 2 hours after meal for 12 weeks in trimester 2 pregnant women with iron deficiency anemia. Method: The research design was a phase IIclinical trial. Subjects were 24 trimester 2 pregnant women with iron deficiency anemia, classified into two groups, who were treated as follows: The first group was consisted of 12 women with irondeficiency anemia, treated with twice-a-day ferrous sulphate tablet @300 mg orally,given shortly after meal for 12 weeks