The frequency and clinicopathological significance of NRAS mutations in primary cutaneous nodular melanoma in Indonesia

• Main Authors: Rinonce, Hanggoro Tri, Sastri, Deflen Jumatul, Trisnawati, Fita, Kameswari, Bidari, Ferronika, Paranita, Irianiwati, Irianiwati
• Format: Article PeerReviewed
• Language: English
• Published: Wiley Periodicals LLC 2022
• Subjects: Pharmacology and Pharmaceutical Sciences
• Online Access: https://repository.ugm.ac.id/278561/1/Rinonce_KKMK.pdf; https://repository.ugm.ac.id/278561/; https://onlinelibrary.wiley.com/doi/epdf/10.1002/cnr2.1454
• Institution: Universitas Gadjah Mada

Background: Melanoma is a lethal skin malignancy with a high risk of metastasis, which prompts a need for research on treatment targets and prognostic factors. Recent studies show that the presence of neuroblastoma RAS viral oncogene homolog (NRAS) mutation can influence cell growth in melanomas. T...