THE ANTIBACTERIALCOMPOUNDCOLLISMICIN A DERIVED FROM MARINE Streptomyces sp Q-629K

ABSTRACT In our course of screening for secondary metabolite derived from marine bacterial, we isolate the antimicrobial compound co/lysmicin A from the ethyl acetate extract of Streptomyces sp Q-629K. Separation of this compound was carried out by silica gel open column chromatography. Purification...

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Main Author: Perpustakaan UGM, i-lib
Format: Article NonPeerReviewed
Published: [Yogyakarta] : Universitas Gadjah Mada 2008
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Online Access:https://repository.ugm.ac.id/27939/
http://i-lib.ugm.ac.id/jurnal/download.php?dataId=11002
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spelling id-ugm-repo.279392014-06-18T00:24:45Z https://repository.ugm.ac.id/27939/ THE ANTIBACTERIALCOMPOUNDCOLLISMICIN A DERIVED FROM MARINE Streptomyces sp Q-629K Perpustakaan UGM, i-lib Jurnal i-lib UGM ABSTRACT In our course of screening for secondary metabolite derived from marine bacterial, we isolate the antimicrobial compound co/lysmicin A from the ethyl acetate extract of Streptomyces sp Q-629K. Separation of this compound was carried out by silica gel open column chromatography. Purification of an active compound was done using HPLC C1Bwith acetonitril-water system. Determinationof chemical structure was done by 1H,13CNMR and LC-MS analysis. Co/lysmicin A was contained in fraction 3, fraction 7.2 and fraction B.7. The antimicrobial assayed from purified compound Fr.B.7 gave diameter inhibition approximately 13 mm against S. aureus and 12 mm against B. subtilis . Keywords: antimicrobial, collismycin A and marine Streptomyces sp. [Yogyakarta] : Universitas Gadjah Mada 2008 Article NonPeerReviewed Perpustakaan UGM, i-lib (2008) THE ANTIBACTERIALCOMPOUNDCOLLISMICIN A DERIVED FROM MARINE Streptomyces sp Q-629K. Jurnal i-lib UGM. http://i-lib.ugm.ac.id/jurnal/download.php?dataId=11002
institution Universitas Gadjah Mada
building UGM Library
country Indonesia
collection Repository Civitas UGM
topic Jurnal i-lib UGM
spellingShingle Jurnal i-lib UGM
Perpustakaan UGM, i-lib
THE ANTIBACTERIALCOMPOUNDCOLLISMICIN A DERIVED FROM MARINE Streptomyces sp Q-629K
description ABSTRACT In our course of screening for secondary metabolite derived from marine bacterial, we isolate the antimicrobial compound co/lysmicin A from the ethyl acetate extract of Streptomyces sp Q-629K. Separation of this compound was carried out by silica gel open column chromatography. Purification of an active compound was done using HPLC C1Bwith acetonitril-water system. Determinationof chemical structure was done by 1H,13CNMR and LC-MS analysis. Co/lysmicin A was contained in fraction 3, fraction 7.2 and fraction B.7. The antimicrobial assayed from purified compound Fr.B.7 gave diameter inhibition approximately 13 mm against S. aureus and 12 mm against B. subtilis . Keywords: antimicrobial, collismycin A and marine Streptomyces sp.
format Article
NonPeerReviewed
author Perpustakaan UGM, i-lib
author_facet Perpustakaan UGM, i-lib
author_sort Perpustakaan UGM, i-lib
title THE ANTIBACTERIALCOMPOUNDCOLLISMICIN A DERIVED FROM MARINE Streptomyces sp Q-629K
title_short THE ANTIBACTERIALCOMPOUNDCOLLISMICIN A DERIVED FROM MARINE Streptomyces sp Q-629K
title_full THE ANTIBACTERIALCOMPOUNDCOLLISMICIN A DERIVED FROM MARINE Streptomyces sp Q-629K
title_fullStr THE ANTIBACTERIALCOMPOUNDCOLLISMICIN A DERIVED FROM MARINE Streptomyces sp Q-629K
title_full_unstemmed THE ANTIBACTERIALCOMPOUNDCOLLISMICIN A DERIVED FROM MARINE Streptomyces sp Q-629K
title_sort antibacterialcompoundcollismicin a derived from marine streptomyces sp q-629k
publisher [Yogyakarta] : Universitas Gadjah Mada
publishDate 2008
url https://repository.ugm.ac.id/27939/
http://i-lib.ugm.ac.id/jurnal/download.php?dataId=11002
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