EFFECTS OF DIETARY ADENINE ON GROWTH, LIPID SECRETION, AND LIVER LIPID CONTENT

ABSTRACT The effects of dietary adenine on growth, lipid secretion, and liver lipid contents were studied. Rats were paired-fed 0.25 %adenine diet or a diet without adenine for 10 days. The final body weight and relative liver weight were recorded. Serum lipid profiles were measured using enzyme ass...

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Main Author: Perpustakaan UGM, i-lib
Format: Article NonPeerReviewed
Published: [Yogyakarta] : Universitas Gadjah Mada 2010
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Online Access:https://repository.ugm.ac.id/28089/
http://i-lib.ugm.ac.id/jurnal/download.php?dataId=11152
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spelling id-ugm-repo.280892014-06-18T00:23:54Z https://repository.ugm.ac.id/28089/ EFFECTS OF DIETARY ADENINE ON GROWTH, LIPID SECRETION, AND LIVER LIPID CONTENT Perpustakaan UGM, i-lib Jurnal i-lib UGM ABSTRACT The effects of dietary adenine on growth, lipid secretion, and liver lipid contents were studied. Rats were paired-fed 0.25 %adenine diet or a diet without adenine for 10 days. The final body weight and relative liver weight were recorded. Serum lipid profiles were measured using enzyme assay kits. Lipids of liver tissues were extracted and the lipid contents were determined. A peach of liver was prepared to determine the activities of fatty acid synthase (FAS) and fatty acid {3-oxidation.The results showed that animals fed an adenine diet reduced slightly body weight and relative liver weight and promoted serum triglyceride (TG), phospholipids (PL), total cholesterol, and high density lipoprotein concentrations. Their promotions were approximately by 74%, 20%, 27%, and 27%, respectively. The liver PL content increased significantly whereas the promotions of liver TG and cholesterol failed to reach significant level. Furthermore, the FAS activity slightly stimulated, but fatty acid {3-oxidation significantly decreased. In conclusion: dietary adenine suppressed slightly growth of body weight and relative liver weight but promoted secretion of lipid compounds from liver tissue into extra-hepaticand liver PL content. The enzyme activity of lipogenic was slightly stimulated whereas the lipolytic was significantly inhibited. Keywords: adenine, serum lipid, triglyceride, high density lipoprotein, cholesterol [Yogyakarta] : Universitas Gadjah Mada 2010 Article NonPeerReviewed Perpustakaan UGM, i-lib (2010) EFFECTS OF DIETARY ADENINE ON GROWTH, LIPID SECRETION, AND LIVER LIPID CONTENT. Jurnal i-lib UGM. http://i-lib.ugm.ac.id/jurnal/download.php?dataId=11152
institution Universitas Gadjah Mada
building UGM Library
country Indonesia
collection Repository Civitas UGM
topic Jurnal i-lib UGM
spellingShingle Jurnal i-lib UGM
Perpustakaan UGM, i-lib
EFFECTS OF DIETARY ADENINE ON GROWTH, LIPID SECRETION, AND LIVER LIPID CONTENT
description ABSTRACT The effects of dietary adenine on growth, lipid secretion, and liver lipid contents were studied. Rats were paired-fed 0.25 %adenine diet or a diet without adenine for 10 days. The final body weight and relative liver weight were recorded. Serum lipid profiles were measured using enzyme assay kits. Lipids of liver tissues were extracted and the lipid contents were determined. A peach of liver was prepared to determine the activities of fatty acid synthase (FAS) and fatty acid {3-oxidation.The results showed that animals fed an adenine diet reduced slightly body weight and relative liver weight and promoted serum triglyceride (TG), phospholipids (PL), total cholesterol, and high density lipoprotein concentrations. Their promotions were approximately by 74%, 20%, 27%, and 27%, respectively. The liver PL content increased significantly whereas the promotions of liver TG and cholesterol failed to reach significant level. Furthermore, the FAS activity slightly stimulated, but fatty acid {3-oxidation significantly decreased. In conclusion: dietary adenine suppressed slightly growth of body weight and relative liver weight but promoted secretion of lipid compounds from liver tissue into extra-hepaticand liver PL content. The enzyme activity of lipogenic was slightly stimulated whereas the lipolytic was significantly inhibited. Keywords: adenine, serum lipid, triglyceride, high density lipoprotein, cholesterol
format Article
NonPeerReviewed
author Perpustakaan UGM, i-lib
author_facet Perpustakaan UGM, i-lib
author_sort Perpustakaan UGM, i-lib
title EFFECTS OF DIETARY ADENINE ON GROWTH, LIPID SECRETION, AND LIVER LIPID CONTENT
title_short EFFECTS OF DIETARY ADENINE ON GROWTH, LIPID SECRETION, AND LIVER LIPID CONTENT
title_full EFFECTS OF DIETARY ADENINE ON GROWTH, LIPID SECRETION, AND LIVER LIPID CONTENT
title_fullStr EFFECTS OF DIETARY ADENINE ON GROWTH, LIPID SECRETION, AND LIVER LIPID CONTENT
title_full_unstemmed EFFECTS OF DIETARY ADENINE ON GROWTH, LIPID SECRETION, AND LIVER LIPID CONTENT
title_sort effects of dietary adenine on growth, lipid secretion, and liver lipid content
publisher [Yogyakarta] : Universitas Gadjah Mada
publishDate 2010
url https://repository.ugm.ac.id/28089/
http://i-lib.ugm.ac.id/jurnal/download.php?dataId=11152
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