Thrombin induces IL-8/CXCL8 expression by DCLK1-dependent RhoA and YAP activation in human lung epithelial cells
Background: Doublecortin‑like kinase 1 (DCLK1) has been recognized as a marker of cancer stem cell in several malignancies. Thrombin is crucial in asthma severity as it can promote IL‑8/CXCL8 production in lung epithelial cells, which is a potent chemoattractant for neutrophils. However, the patho...
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| Main Authors: | , , , , , |
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| Format: | Article PeerReviewed |
| Language: | English |
| Published: |
Springer Nature
2022
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| Subjects: | |
| Online Access: | https://repository.ugm.ac.id/282842/1/209.pdf https://repository.ugm.ac.id/282842/ https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929-022-00877-0 |
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| Institution: | Universitas Gadjah Mada |
| Language: | English |