Physiologically based pharmacokinetic model predictions of natural product-drug interactions between goldenseal, berberine, imatinib and bosutinib
Purpose: This study implements a physiologically based pharmacokinetic (PBPK) modelling approach to predict the effect of hydrastine and berberine, two major alkaloids present in goldenseal extract, on pharmacokinetics of imatinib and bosutinib. Methods: PBPK models of hydrastine and berberine were...
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| Main Authors: | , , |
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| Format: | Article PeerReviewed |
| Language: | English |
| Published: |
Springer Science and Business Media Deutschland GmbH
2022
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| Subjects: | |
| Online Access: | https://repository.ugm.ac.id/283068/1/Physiologically%20based%20pharmacokinetic%20model%20predictions%20of%20natural%20product-drug%20interactions%20between%20goldenseal%2C%20berberine%2C%20imatinib%20and%20bosutinib.pdf https://repository.ugm.ac.id/283068/ https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123083703&doi=10.1007%2fs00228-021-03266-y&partnerID=40&md5=80ba99ea75d46cb5070d02a79635dcec |
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| Institution: | Universitas Gadjah Mada |
| Language: | English |
Internet
https://repository.ugm.ac.id/283068/1/Physiologically%20based%20pharmacokinetic%20model%20predictions%20of%20natural%20product-drug%20interactions%20between%20goldenseal%2C%20berberine%2C%20imatinib%20and%20bosutinib.pdfhttps://repository.ugm.ac.id/283068/
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123083703&doi=10.1007%2fs00228-021-03266-y&partnerID=40&md5=80ba99ea75d46cb5070d02a79635dcec