Prevalence of diabetes in pregnancy and microvascular complications in native Indonesian women: The Jogjakarta diabetic retinopathy initiatives in pregnancy (Jog-DRIP)
Objectives: To report the prevalence of total diabetes in pregnancy (TDP) and diabetes-related microvascular complications among Indonesian pregnant women. Methods: We conducted a community-based cross-sectional study with multi-stage, cluster random sampling to select the participating community h...
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id-ugm-repo.2833062023-11-20T06:55:00Z https://repository.ugm.ac.id/283306/ Prevalence of diabetes in pregnancy and microvascular complications in native Indonesian women: The Jogjakarta diabetic retinopathy initiatives in pregnancy (Jog-DRIP) Widyaputri, Felicia Lim, Lyndell L. Utami, Tiara Putri Harti, Annisa Pelita Agni, Angela Nurini Nurdiati, Detty Siti Widayanti, Tri Wahyu Supanji, Supanji Wardhana, Firman Setya Prayogo, Muhammad Eko Sasongko, Muhammad Bayu Obstetrics and Gynaecology Optometry and Ophthalmology Objectives: To report the prevalence of total diabetes in pregnancy (TDP) and diabetes-related microvascular complications among Indonesian pregnant women. Methods: We conducted a community-based cross-sectional study with multi-stage, cluster random sampling to select the participating community health centers (CHC) in Jogjakarta, Indonesia between July 2018-November 2019. All pregnant women in any trimester of pregnancy within the designated CHC catchment area were recruited. Capillary fasting blood glucose (FBG) and blood glucose (BG) at 1-hour (1-h), and 2-hour (2-h) post oral glucose tolerance test (OGTT) were measured. TDP was defined as the presence of pre-existing diabetes or diabetes in pregnancy (FBG ≥7.0 mmol/L, or 2-h OGTT ≥11.1 mmol/L, or random BG ≥11.1 mmol/L with diabetes symptoms). Disc and macula-centered retinal photographs were captured to assess diabetic retinopathy (DR). Blood pressure, HbA1c and serum creatinine levels were also measured. Results: A total of 631/664 (95%) eligible pregnant women were included. The median age was 29 (IQR 26–34) years. The prevalence of TDP was 1.1% (95%CI 0.5, 2.3). It was more common in women with chronic hypertension (p = 0.028) and a family history of diabetes (p = 0.015). Among the TDP group, 71% had a high HbA1c, but no DR nor nephropathy were observed. Conclusions: Although a very low prevalence of TDP and no diabetes-related microvascular complications were documented in this population, there is still a need for a screening program for diabetes in pregnancy. Once diabetes has been identified, appropriate management can then be provided to prevent adverse outcomes. Public Library of Science 2022-06 Article PeerReviewed application/pdf en https://repository.ugm.ac.id/283306/1/Felicia%20Widyaputri_Prevalence%20of%20diabetes%20in%20pregnancy.pdf Widyaputri, Felicia and Lim, Lyndell L. and Utami, Tiara Putri and Harti, Annisa Pelita and Agni, Angela Nurini and Nurdiati, Detty Siti and Widayanti, Tri Wahyu and Supanji, Supanji and Wardhana, Firman Setya and Prayogo, Muhammad Eko and Sasongko, Muhammad Bayu (2022) Prevalence of diabetes in pregnancy and microvascular complications in native Indonesian women: The Jogjakarta diabetic retinopathy initiatives in pregnancy (Jog-DRIP). PLOS ONE, 17 (e02676). pp. 1-11. ISSN 19326203 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0267663 10.1371/journal.pone.0267663 |
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Obstetrics and Gynaecology Optometry and Ophthalmology Widyaputri, Felicia Lim, Lyndell L. Utami, Tiara Putri Harti, Annisa Pelita Agni, Angela Nurini Nurdiati, Detty Siti Widayanti, Tri Wahyu Supanji, Supanji Wardhana, Firman Setya Prayogo, Muhammad Eko Sasongko, Muhammad Bayu Prevalence of diabetes in pregnancy and microvascular complications in native Indonesian women: The Jogjakarta diabetic retinopathy initiatives in pregnancy (Jog-DRIP) |
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Objectives: To report the prevalence of total diabetes in pregnancy (TDP) and diabetes-related microvascular complications among Indonesian pregnant women.
Methods: We conducted a community-based cross-sectional study with multi-stage, cluster random sampling to select the participating community health centers (CHC) in Jogjakarta, Indonesia between July 2018-November 2019. All pregnant women in any trimester of pregnancy within the designated CHC catchment area were recruited. Capillary fasting blood glucose (FBG) and blood glucose (BG) at 1-hour (1-h), and 2-hour (2-h) post oral glucose tolerance test (OGTT) were measured. TDP was defined as the presence of pre-existing diabetes or diabetes in pregnancy (FBG ≥7.0 mmol/L, or 2-h OGTT ≥11.1 mmol/L, or random BG ≥11.1 mmol/L with diabetes symptoms). Disc and macula-centered retinal photographs were captured to assess diabetic retinopathy (DR). Blood pressure, HbA1c and serum creatinine levels were also measured.
Results: A total of 631/664 (95%) eligible pregnant women were included. The median age was 29 (IQR 26–34) years. The prevalence of TDP was 1.1% (95%CI 0.5, 2.3). It was more common in women with chronic hypertension (p = 0.028) and a family history of diabetes (p = 0.015). Among the TDP group, 71% had a high HbA1c, but no DR nor nephropathy were observed.
Conclusions: Although a very low prevalence of TDP and no diabetes-related microvascular complications were documented in this population, there is still a need for a screening program for diabetes in pregnancy. Once diabetes has been identified, appropriate management can then be provided to prevent adverse outcomes. |
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Article PeerReviewed |
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Widyaputri, Felicia Lim, Lyndell L. Utami, Tiara Putri Harti, Annisa Pelita Agni, Angela Nurini Nurdiati, Detty Siti Widayanti, Tri Wahyu Supanji, Supanji Wardhana, Firman Setya Prayogo, Muhammad Eko Sasongko, Muhammad Bayu |
author_facet |
Widyaputri, Felicia Lim, Lyndell L. Utami, Tiara Putri Harti, Annisa Pelita Agni, Angela Nurini Nurdiati, Detty Siti Widayanti, Tri Wahyu Supanji, Supanji Wardhana, Firman Setya Prayogo, Muhammad Eko Sasongko, Muhammad Bayu |
author_sort |
Widyaputri, Felicia |
title |
Prevalence of diabetes in pregnancy and microvascular complications in native Indonesian women: The Jogjakarta diabetic retinopathy initiatives in pregnancy (Jog-DRIP) |
title_short |
Prevalence of diabetes in pregnancy and microvascular complications in native Indonesian women: The Jogjakarta diabetic retinopathy initiatives in pregnancy (Jog-DRIP) |
title_full |
Prevalence of diabetes in pregnancy and microvascular complications in native Indonesian women: The Jogjakarta diabetic retinopathy initiatives in pregnancy (Jog-DRIP) |
title_fullStr |
Prevalence of diabetes in pregnancy and microvascular complications in native Indonesian women: The Jogjakarta diabetic retinopathy initiatives in pregnancy (Jog-DRIP) |
title_full_unstemmed |
Prevalence of diabetes in pregnancy and microvascular complications in native Indonesian women: The Jogjakarta diabetic retinopathy initiatives in pregnancy (Jog-DRIP) |
title_sort |
prevalence of diabetes in pregnancy and microvascular complications in native indonesian women: the jogjakarta diabetic retinopathy initiatives in pregnancy (jog-drip) |
publisher |
Public Library of Science |
publishDate |
2022 |
url |
https://repository.ugm.ac.id/283306/1/Felicia%20Widyaputri_Prevalence%20of%20diabetes%20in%20pregnancy.pdf https://repository.ugm.ac.id/283306/ https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0267663 |
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1783956423747567616 |