Pharmacophore-guided Virtual Screening to Identify New β3-adrenergic Receptor Agonists
The β3-adrenergic receptor (β3-AR) is found in several tissues such as adipose tissue and urinary bladder. It is a therapeutic target because it plays a role in thermogenesis, lipolysis, and bladder relaxation. Two β3-AR agonists are used clinically: mirabegron 1 and vibegron 2, which are indicated...
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| Main Authors: | , , , , , , |
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| Format: | Article PeerReviewed |
| Language: | English |
| Published: |
John Wiley and Sons Inc
2022
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| Subjects: | |
| Online Access: | https://repository.ugm.ac.id/283359/1/55_Pharmacophore-guided%20Virtual%20Screening%20to%20Identify%20New%20%CE%B23-adrenergic%20Receptor%20Agonists.pdf https://repository.ugm.ac.id/283359/ https://www.scopus.com/inward/record.uri?eid=2-s2.0-85124069779&doi=10.1002%2fminf.202100223&partnerID=40&md5=171ff1139360e5a4d2b1bd3874af1a46 |
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| Institution: | Universitas Gadjah Mada |
| Language: | English |