Standardised Ethanol Extract of Tithonia diversifolia (Hemsley) A Gray Leaves Improve Insulin Sensitivity and Increase Mitochondrial DNA Copy Numbers in Skeletal Muscles of Streptozotocin-Nicotinamide-Induced Rats

• Main Authors: Istikharah, Rochmy, Nugrahaningsih, Dwi Aris Agung, Sadewa, Ahmad Hamim, Wahyuningsih, Mae Sri Hartati
• Format: Article PeerReviewed
• Language: English
• Published: Penerbit Universiti Sains Malaysia 2022
• Subjects: Pharmaceutical Sciences; Pharmacology and Pharmaceutical Sciences
• Online Access: https://repository.ugm.ac.id/283581/1/Rochmy%20Istikharah_Standardised%20ethanol.pdf; https://repository.ugm.ac.id/283581/; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249416/
• Institution: Universitas Gadjah Mada

Background: In this study, we examined the anti-diabetic activity of standardised extracts of Tithonia diversifolia (Hemsley) A Gray (T. diversifolia) leaves for their effects on insulin resistance and mitochondrial DNA (mtDNA) copy number. Methods: T. diversifolia leaves were extracted using an ult...