The role of Phosphodiesterase-1 and its natural product inhibitors in Alzheimer’s disease: A review

Phosphodiesterase-1 (PDE1) is a versatile enzyme that has surprisingly received considerable attention as a possible therapeutic target in Alzheimer’s disease (AD) because it maintains the homeostasis of 3ʹ,5ʹ-cyclic adenosine monophosphate (cAMP) and 3ʹ,5ʹ-cyclic guanosine monophosphate (cGMP) in t...

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Main Authors: Ahmad, Nazir, Lesa, Kaisun Nesa, Sudarmanto, Ari, Fakhrudin, Nanang, Ikawati, Zullies
Format: Article PeerReviewed
Language:English
Published: Frontiers Media S.A. 2022
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Online Access:https://repository.ugm.ac.id/283695/1/The%20role%20of%20Phosphodiesterase-1%20and%20its%20natural%20product%20inhibitors%20in%20Alzheimer%E2%80%99s%20disease.pdf
https://repository.ugm.ac.id/283695/
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85145506576&doi=10.3389%2ffphar.2022.1070677&partnerID=40&md5=354b79d953e880a46a1dc4684eff0d7f
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Institution: Universitas Gadjah Mada
Language: English