Substituted 3-styryl-2-pyrazoline Derivatives as an Antimalaria: Synthesis, in vitro Assay, Molecular Docking, Druglikeness Analysis, and ADMET Prediction (Penggantian Terbitan 3-styryl-2-pyrazoline sebagai Antimalaria: Sintesis, Asai in vitro, Dok Molekul, Analisis Keserupaan Dadah dan Ramalan ADMET

• Main Authors: Ekawati, Linda, Nurohmah, Beta Achromi, Syahri, Jufrizal, Purwono, Bambang
• Format: Other NonPeerReviewed
• Language: English
• Published: Sains Malaysiana 2022
• Subjects: Physical Chemistry
• Online Access: https://repository.ugm.ac.id/283741/1/Substituted-3styryl2pyrazoline-Derivatives-as-an-Antimalaria-Synthesis-in-vitro-Assay-Molecular-Docking-Druglikeness-Analysis-and-ADMET-PredictionSains-Malaysiana.pdf; https://repository.ugm.ac.id/283741/; https://www.ukm.my/jsm/pdf_files/SM-PDF-51-10-2022/9.pdf; http://doi.org/10.17576/jsm-2022-5110-09
• Institution: Universitas Gadjah Mada

The synthesis, in vitro antimalarial assay, molecular docking, drug-likeness analysis, and ADMET prediction of substituted 3-styryl-2-pyrazoline derivatives as antimalaria have been conducted. The synthesis of N-phenyl (1a‒3a) and N-acetyl-substituted (1b‒3b) 3-styryl-2-pyrazolines was carried out...