Effect of Nuclear Export Inhibitor Leptomycin Bon the Intracellular Localization of HBV Core Protein into Hepatocytes Cell Line Huh-7 and HepG2 Cells

• Main Author: Perpustakaan UGM, i-lib
• Format: Article NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2010
• Subjects: Jurnal i-lib UGM
• Online Access: https://repository.ugm.ac.id/28894/; http://i-lib.ugm.ac.id/jurnal/download.php?dataId=11957
• Institution: Universitas Gadjah Mada

Leptomycin B (LMB) was originally discovered as a potent anti-fungal antibiotic from Streptomyces species. The cellular target of LMBhas been identified as the nuclear export receptor CRM-1 or exportin-1, which is involved in nuclear trafficking of cellular RNAs or proteins containing the nuclear ex...