QSAR MODELING OF 2-[CH(OH)X]-S,8-(OYh-l,4- NAPHTHOQUININES AGAINST L12l0 CELLS USING MULTIPLE LINEAR REGRESSION
Quinones are present in many drugs such as anthracyclines, daunorubicin, doxorubicin, mitomycin, mitoxantrones and saintopin, which are used clinically in the therapy of solid cancers. The cytotoxic effects of these quinone are mainly due to the inhibition of DNA topoisomerase-II. It is the necessit...
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| Format: | Article NonPeerReviewed |
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[Yogyakarta] : Universitas Gadjah Mada
2012
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| Online Access: | https://repository.ugm.ac.id/29177/ http://i-lib.ugm.ac.id/jurnal/download.php?dataId=12240 |
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| Institution: | Universitas Gadjah Mada |