KUALITAS HIDUP PENDERITA KANKER PAYUDARA STADIUM AWAL YANG MENDAPAT KEMOTERAPI AJUVAN BERBASIS ANTRASIKLIN

• Main Authors: , Erna Fitrisia Chistina, dr, , dr. Johan Kurnianda,. Sp. PD.KHOM.
• Format: Theses and Dissertations NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2011
• Subjects: ETD
• Online Access: https://repository.ugm.ac.id/39021/; http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=50169
• Institution: Universitas Gadjah Mada

Breast cancer, is the leading cause of cancer among women around the world and second leading cause of cancer deaths. Adjuvant chemotherapy has proved useful to treat breast cancer. Anthracycline-based regimen have been proven and effective in adjuvant chemothetapy of breast cancer. Decision to give adjuvant chemotherapy not only including data on reccurence, survival dan acut toxicity but also quality of life. Sosiodemographic factors such as age, education, ocupation, marital status also have a relationship with quality of life. This study used cohort design observing early stage breast cancer patients who receive anthracycline-based regimen chemotherapy. This study compared the changes of FACT-B score before chemotherapy, with durante chemotherapy, after complete chemotherapy IV and 3 months after complete chemotherapy cycles. The better score FACT-B reflects the better quality of life. Further analysis will be done to determine other factors that influences the changes of FACT-B score. 40 subjects eligible to the criteria, with mean age was 48,30±6,89 tahun. Most of the subjects were highschool and college, 24 subjects (60%). 22 subjects (55%) still have their menstruation. Stadium II were 28 subjects (70%), stadium III were 12 subjects (30%). Regimen AC was used in 36 subjects (90%). There was increasing in FACT-B score after completed chemotherapy cycle compared with FACT-B score before chemotherapy, and was statistically significant (p=0,001). There was no difference in FACT-B score that statistically significant in age, tumour stadium, menopausal status, education, occupation. Early stage breast cancer subjects receive anthracyclin based regimen of adjuvant chemotherapy had better quality of life 3 months after complete chemotherapy cycles. The better FACT-B score were not influences by age, menopausal status, tumour stadium, education, and occupation.