VALIDITAS DIAGNOSTIK MIKRODIFUSI CONWAY YANG DIMODIFIKASI PADA PEMERIKSAAN ALKOHOL DARAH

Ethanol (CH3-CH2-OH) is common to find in alcoholic drink. Ethanol has already been used by human beings since pre historical time and often cause toxicity. Determination of postmortem blood ethanol concentration is one of important and the most frequent analysis in forensic toxicology laboratory. M...

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Bibliographic Details
Main Authors: , R. Dirwan Suryo Soularto, dr., , dr. IBG Surya Putra Pidada, Sp.F.
Format: Theses and Dissertations NonPeerReviewed
Published: [Yogyakarta] : Universitas Gadjah Mada 2011
Subjects:
ETD
Online Access:https://repository.ugm.ac.id/88405/
http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=50520
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Institution: Universitas Gadjah Mada
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Summary:Ethanol (CH3-CH2-OH) is common to find in alcoholic drink. Ethanol has already been used by human beings since pre historical time and often cause toxicity. Determination of postmortem blood ethanol concentration is one of important and the most frequent analysis in forensic toxicology laboratory. Modified Conway Microdiffusion method is semi quantitative identification that may able to detect blood ethanol concentration. This is one of old medical technology that still used in forensic toxicology laboratory because it is cheap, easy and quick. Conway Microdiffusion method is modified to measure blood ethanol concentration for victim died from motorvehicle accidents in order to know its validity. This research used cross-sectional design. Validity of modified Conway Microdiffusion method for blood ethanol concentrations is compared with gas chromatographic examination as the gold standard. The blood sample examine at the laboratory by modified Conway Microdiffusion method and also tested by gas chromatograpic for blood ethanol concentration independently and blindly. Diagnosis of the use of ethanol is defined if the blood ethanol concentration more than 0,0 mg%. Statistical analysis is performed using SPSS 10.0. The clinical sensitivity, specificity, positive and negative predictive value, accuracy and likelihood ratio are calculated by 2x2 table. Determination of blood ethanol concentration by modified Conway Microdiffusion method is expected to be beneficial in the examination and visum et repertum making for victim died from motorvehicle accidents.