PERBEDAAN RERATA PENURUNAN KUALITAS HIDUP ANTAR DERAJAT MUKOSITIS PADA PENDERITA KANKER NASOFARINGS YANG MENDAPAT TERAPI STANDAR
Nasopharynx cancer is often happened in China and South-East Asia. In Indonesia, especially in south region of Central Java, undifferentiated carcinoma is the most often cancer type of head and neck and 5th most prevalence type of cancer as a whole. In Yogyakarta province, hospital-based data sho...
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| Format: | Theses and Dissertations NonPeerReviewed |
| Published: |
[Yogyakarta] : Universitas Gadjah Mada
2013
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| Subjects: | |
| Online Access: | https://repository.ugm.ac.id/88916/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=51282 |
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| Institution: | Universitas Gadjah Mada |
| Summary: | Nasopharynx cancer is often happened in China and South-East Asia.
In Indonesia, especially in south region of Central Java, undifferentiated
carcinoma is the most often cancer type of head and neck and 5th most prevalence
type of cancer as a whole. In Yogyakarta province, hospital-based data show
nasopharynx cancer as number one cancer for male and number 3 for female.
Mucositis is an inflammation and irritation of digestive mucous membrane as the
effect of damage in basal cell squamous epithelial proliferation system. It can
arises from radiotherapy and chemotherapy which is cytotoxic. Typical sigh
related to mucositis is pain and difficulty swallowing, eating and drinking and
also trouble in ability to speaking and communicating. Mucositis give impact to
quality of treatment and life.
In recent time, there is no data showing the relation between the
degrees of mucositis with the degradation of quality of life at nasopharynx cancer
patient experiencing concurrent chemoradiation therapy (CCRT). The objective of
this study is to know the difference average of degradation in quality of life for
each degree of mucositis at nasopharynx cancer patients with standard therapy
The subjects of this study are all nasopharynx cancer patients who
receiving CCRT from Yogyakarta and surrounding area in Internal Ward and
Tulip Cancer Center, Sardjito General Hospital Yogyakarta during the month of
January 2011 up to December 2011 who fulfilling the inclusion criteria. Subjects
were noted their age and gender, is there any mucositis and its degree, their body
weight, hemoglobin. After that they have to fill the Indonesian version FACT
H&N questioner before starting the CCRT, after third cycle and by the end of
CCRT. This study is a time series. Statistical analysis which done is to look for
the difference average of degradation in quality of life between each degree of
mucositis using Anova test. Accepted significance if p < 0,05 |
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