PENGARUH HIPOKSIA HIPOBARIK TERHADAP FUNGSI SEL RAMBUT LUAR KOKHLEA

• Main Authors: , Slamet Widodo, dr, , Dr. D.A. Edhie Samodra, Sp.THT-KL(K)
• Format: Theses and Dissertations NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2011
• Subjects: ETD
• Online Access: https://repository.ugm.ac.id/88921/; http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=51286
• Institution: Universitas Gadjah Mada

Cochlear hair cell is a sensoric cell of hearing system with a hair like structrure above it, which is a stereocilia. Cochlea is an organ that works continuously for 24 hours a day, receiving vascularization from a very small artery (a.cochlearis) without collateral and vasculary striae which is the prime energy for hair cells in organon Corti. Hypoxic condition can cause damage to the cell in human body. Cochlear outer hair cell is one of the cell that wont regenerate after receiving a damage, while this cell is very crucial for hearing process to work well. People who are frequently traveled by airplane, or pilot cadets, receiving a hypoxic hypobaric condition pretty often. This means that as a pilot cadets, they would have to endure a certain hypoxic hypobaric condition during training in the hypobaric chamber. The purpose of this study is to know the effects of hypoxic hypobaric condition in 18.000 feet high, to the pilot cadet�s outer cochlear hair cell function. The design of this study is quasi experimental. Statistical analysis using numerical calculation such as mean, deviation standart, and percentage. t-test also used to compare the mean of pre and post test in time series. The result of this study showed that there were 9 subject (18%) with cochlear outer hair cell function abnormality after 5 minutes inside the chamber, and after 25 minutes there were 16 subject (32%) with same abnormality. Blood oxygen saturation before and after 5 minutes and 25 minutes had significant difference (p<0,01). Mean of the blood oxygen saturation after 5 minute (71,42 SD 1,401) and after 25 minute (71,22 SD 1,329). Almost every parameter showed significant different before and after 5 minutes and befora and after 25 minutes in hypobarec chamber (p<0,05), except NF with 3 Khz frequencies (p>0,05). The SNR value in every frequencies was still above 6 dB, which mean that cochlear outer haircell still function normally. In conclusion cochlear outer haircell function was decreasing due to acute hypoxia in 18.000 ft.