KORELASI ANGKA CD4 DENGAN JUMLAH REFLEKS PRIMITIF PADA PENDERITA HUMAN IMMUNODEFICIENCY VIRUS (HIV)
Background: Infection with HIV is an immune system disorder that causes disturbances in the infected human body systems, including nervous system disorders. CD4 T-lymphocytes regulate the human immune system, thus the number tends to decline in HIV infection.Complications of cognitive impairment occ...
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Main Authors: | , |
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Format: | Theses and Dissertations NonPeerReviewed |
Published: |
[Yogyakarta] : Universitas Gadjah Mada
2011
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Subjects: | |
Online Access: | https://repository.ugm.ac.id/89595/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=51863 |
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Institution: | Universitas Gadjah Mada |
Summary: | Background: Infection with HIV is an immune system disorder that causes
disturbances in the infected human body systems, including nervous system
disorders. CD4 T-lymphocytes regulate the human immune system, thus the number
tends to decline in HIV infection.Complications of cognitive impairment occurs in
30-50% of individuals infected with HIV. Primitive reflex associated with cognitive
impairment, including dementia.
Objectives: To determine the number of CD4 to determine the relationship of
primitive reflexes in individuals infected with the HIV virus.
Methods: This study used cross-sectional study design (cross-sectional). Population
studies are all HIV positive patients who had CD4 numbers are still undergoing
treatment at RSUP Dr. Sardjito and the eligibilitas criteria of sampling by consecutive
sampling. Primitive reflexes were examined in the form of Glabella reflex, snout
reflex, Palmomental reflex, Graps reflex, reflex Suck, Babinsky reflex, Rossolimo
reflex, and Nuchocephalic reflex. Assessment of cognitive impairment using the
MMSE test.
Results: The study found 96 people living with HIV. Data Analysis 66(68.75%)
male, female 30(31.25%). Highest average age at 31.30(SD ± 6.54) years. Highest
percentage of education level high school educated 45(46.87%). Figures obtained a
mean CD4 cell count 215.52(SD±195.63). Primitive reflexes were examined as eight
kinds of primitive reflexes obtained averages of 2.72(SD± 1.62%). Spearman's
correlation test showed a correlation between the number of CD4 with primitive
reflex is meaningful.Correlation value of -0.444 indicates the direction of a negative
correlation with the strength of the correlation is.
Conclusion: Based on this study there is significant correlation between the number
of CD4 with primitive reflexes in patients with HIV who were treated at the clinic of
Edelweis RSUP Dr. Sardjito with the strength and direction of the correlation is
negative, so the lower the CD4 cell numbers, the more primitive reflexes were found. |
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