EFFECT OF ATP BINDING CASETTE SUBFAMILY B MEMBER 1, 5-HYDROXYTRIPTAMINE -3B RECEPTOR AND CYP2D6 GENE POLYMORPHISMS AND SOME RISK FACTORS TO THE ANTIEMETICS RESPONSE THERAPY IN CANCER PATIENTS WITH HIGHLY EMETOGENIC CYTOTOXIC DRUG IN DR. SARDJITO HOSPITAL YOGYAKARTA

• Main Authors: , Dyah Aryani Perwitasari, M.Si.,Apt., , Prof. dr. M. Hakimi, Ph.D.,Sp.OG(K)
• Format: Theses and Dissertations NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2011
• Subjects: ETD
• Online Access: https://repository.ugm.ac.id/90703/; http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=52447
• Institution: Universitas Gadjah Mada

Nausea and vomiting are the most distressful side effects of cytotoxic drugs in cancer patients. However, the current antiemetic efficacy is about 70%-80% in patients treated with highly-emetogenic cytotoxic drugs. One of the potential factors explaining this suboptimal response is variability in ge...