ANALISIS KESTABILAN PADA MODEL INFEKSI VIRUS HEPATITIS B DENGAN TERAPI OBAT INTERFERON

In this thesis, a mathematical model consisting of two system is designed. One system is the model with four state variables: uninfected cells, infected cells, free virus and cytotoxic cells, which represent the viral dynamics in hepatitis B virus infection during the interferon therapy. The other s...

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Bibliographic Details
Main Authors: , SULASTRI, S.PD., , Prof. Dr. Widodo, MS
Format: Theses and Dissertations NonPeerReviewed
Published: [Yogyakarta] : Universitas Gadjah Mada 2012
Subjects:
ETD
Online Access:https://repository.ugm.ac.id/99440/
http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=55237
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Institution: Universitas Gadjah Mada
Description
Summary:In this thesis, a mathematical model consisting of two system is designed. One system is the model with four state variables: uninfected cells, infected cells, free virus and cytotoxic cells, which represent the viral dynamics in hepatitis B virus infection during the interferon therapy. The other system is the model proposed by Nowak which describes the viral dynamics in hepatitis B virus infection after stopping the interferon treatment. The system was investigated for looking the basic reproduction number and stability of models. Simulation given ilustration figures for fixed parameter