Structural changes and the differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor kB ligand (RANKL) in subchondral bone during the development of osteoarthritis

• Main Authors: Akma Azmiera Akman, Ain Aisyah Talib, Azirah Md Yusof, Kamarul Ariffin Khalid, Nurul Asyiqin Yusof, Radiah Abdul Ghani, Asmah Hanim Hamdan, Zaitunnatakhin Zamli
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2018
• Online Access: http://journalarticle.ukm.my/12761/1/47_06_11.pdf; http://journalarticle.ukm.my/12761/; http://mabjournal.com/index.php?option=com_content&view=article&id=862&catid=59:current-view&Itemid=56
• Institution: Universiti Kebangsaan Malaysia

Osteoarthritis is a degenerative joint disease that is characterized by subchondral bone changes. These changes may be associated with bone remodelling, which involve coordinative functions between bone formation and resorption markers such as osteoprotegerin (OPG) and receptor activator of nuclea...