Multi-generational culture of c. elegans on a long-term space flight revealed changes in expression of genes involved in longevity, DNA repair,and locomotion

• Main Authors: Sue, Mian Then, Nurul-Faizah Jusoh, Roslan Harun, Sheila Nathan, Szewczyk, Nathaniel J., Stodieck, Louis, Rahman Jamal
• Format: Article
• Language: English
• Published: Pusat Perubatan Universiti Kebangsaan Malaysia 2014
• Online Access: http://journalarticle.ukm.my/13238/1/20-42-1-SM.pdf; http://journalarticle.ukm.my/13238/; http://spaj.ukm.my/apjmm/index.php/apjmm/issue/view/9
• Institution: Universiti Kebangsaan Malaysia

Scientists are trying to determine the long term effects of exposure to microgravity and space radiation on various cellular and biological functions. We used C. elegans as the model organism to study the changes in gene expression. Wild type worms were grown in a liquid medium using the CHab hardwa...