The effect of Stichopus chloronotus aqueous extract on human osteoarthritis articular chondrocytes in three-dimensional collagen type I hydrogel in vitro

• Main Authors: Mohd Heikal Mohd Yunus, Ahmad Nazrun Shuid, Mohd Fauzi Busra, Chua, Kien Hui, Norzana Abdul Ghafar, Rizal Abd Rani
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2019
• Online Access: http://journalarticle.ukm.my/13890/1/13%20Mohd%20Heikal%20Mohd%20Yunus.pdf; http://journalarticle.ukm.my/13890/; http://www.ukm.my/jsm/malay_journals/jilid48bil8_2019/KandunganJilid48Bil8_2019.html
• Institution: Universiti Kebangsaan Malaysia

Autologous chondrocyte-seeded scaffolds have proved to be one of the most promising alternative therapies for articular cartilage defects. However, the chondrocytes have specific nutritional requirements and risk of dedifferentiation during in vitro expansion. Stichopus chloronotus aqueous extract (...