Formulation and evaluation of natural anti Candida albicans ointment containing mango leaf (Mangifera indica L.) extract
Arumanis mango is one of plants potentially used as a medicine. Arumanis mango leaf is potentially used as antimicrobial, which are as antibacterial and antifungal. Mango leaf extracts are able to inhibit Candida albicans with inhibition zone of 8.12 mm. The use of extracts for various purposes has...
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Penerbit Universiti Kebangsaan Malaysia
2019
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my-ukm.journal.143442020-03-03T08:00:17Z http://journalarticle.ukm.my/14344/ Formulation and evaluation of natural anti Candida albicans ointment containing mango leaf (Mangifera indica L.) extract Dian Riana Ningsih, Purwati, Zusfahair, Filliani Akanadewi, Arumanis mango is one of plants potentially used as a medicine. Arumanis mango leaf is potentially used as antimicrobial, which are as antibacterial and antifungal. Mango leaf extracts are able to inhibit Candida albicans with inhibition zone of 8.12 mm. The use of extracts for various purposes has disadvantages. This research aims to formulate ointments dosage from mango leaf extracts, to know its physical properties and its activity against Candida albicans. Antifungal activity test is conducted using diffusion method. The fungus used is Candida albicans. The absorbent ointment preparations has homogeneous semisolid form, yellowish white color, and distinctive odor. The ointment preparations has dispersive power value of 4.90-6.23 cm, adhesiveness of 2.0-7.0 seconds, pH value of 6.56-6.99 and able to protect skin from the outside environment. Inhibition zone of absorbent ointment with concentrations of 30, 65, and 125 ppm, respectively, was 3.07; 5.96; and 9.51 mm. Penerbit Universiti Kebangsaan Malaysia 2019-09 Article NonPeerReviewed application/pdf en http://journalarticle.ukm.my/14344/1/11%20Dian%20Riana%20Ningsih.pdf Dian Riana Ningsih, and Purwati, and Zusfahair, and Filliani Akanadewi, (2019) Formulation and evaluation of natural anti Candida albicans ointment containing mango leaf (Mangifera indica L.) extract. Sains Malaysiana, 48 (9). pp. 1907-1912. ISSN 0126-6039 http://www.ukm.my/jsm/malay_journals/jilid48bil9_2019/KandunganJilid48Bil9_2019.html |
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Arumanis mango is one of plants potentially used as a medicine. Arumanis mango leaf is potentially used as antimicrobial, which are as antibacterial and antifungal. Mango leaf extracts are able to inhibit Candida albicans with inhibition zone of 8.12 mm. The use of extracts for various purposes has disadvantages. This research aims to formulate ointments dosage from mango leaf extracts, to know its physical properties and its activity against Candida albicans. Antifungal activity test is conducted using diffusion method. The fungus used is Candida albicans. The absorbent ointment preparations has homogeneous semisolid form, yellowish white color, and distinctive odor. The ointment preparations has dispersive power value of 4.90-6.23 cm, adhesiveness of 2.0-7.0 seconds, pH value of 6.56-6.99 and able to protect skin from the outside environment. Inhibition zone of absorbent ointment with concentrations of 30, 65, and 125 ppm, respectively, was 3.07; 5.96; and 9.51 mm. |
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Dian Riana Ningsih, Purwati, Zusfahair, Filliani Akanadewi, |
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Dian Riana Ningsih, Purwati, Zusfahair, Filliani Akanadewi, Formulation and evaluation of natural anti Candida albicans ointment containing mango leaf (Mangifera indica L.) extract |
author_facet |
Dian Riana Ningsih, Purwati, Zusfahair, Filliani Akanadewi, |
author_sort |
Dian Riana Ningsih, |
title |
Formulation and evaluation of natural anti Candida albicans ointment containing mango leaf (Mangifera indica L.) extract |
title_short |
Formulation and evaluation of natural anti Candida albicans ointment containing mango leaf (Mangifera indica L.) extract |
title_full |
Formulation and evaluation of natural anti Candida albicans ointment containing mango leaf (Mangifera indica L.) extract |
title_fullStr |
Formulation and evaluation of natural anti Candida albicans ointment containing mango leaf (Mangifera indica L.) extract |
title_full_unstemmed |
Formulation and evaluation of natural anti Candida albicans ointment containing mango leaf (Mangifera indica L.) extract |
title_sort |
formulation and evaluation of natural anti candida albicans ointment containing mango leaf (mangifera indica l.) extract |
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Penerbit Universiti Kebangsaan Malaysia |
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2019 |
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http://journalarticle.ukm.my/14344/1/11%20Dian%20Riana%20Ningsih.pdf http://journalarticle.ukm.my/14344/ http://www.ukm.my/jsm/malay_journals/jilid48bil9_2019/KandunganJilid48Bil9_2019.html |
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