Circulating neonatal Nav1.5 (nNav1.5) antigen and anti-nNav1.5 antibodies as potential biomarkers for breast cancer metastasis

• Main Authors: Harishini Rajaratinam, Nur Syahmina Rasudin, Maya Mazuwin Yahya, Wan Zainira Wan Zain, Sabreena Safuan, Nurul Asma-Abdullah, Noor Fatmawati Mokhtar, Wan Ezumi Mohd Fuad
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2022
• Online Access: http://journalarticle.ukm.my/20650/1/18.pdf; http://journalarticle.ukm.my/20650/; https://www.ukm.my/jsm/malay_journals/jilid51bil9_2022/KandunganJilid51Bil9_2022.html
• Institution: Universiti Kebangsaan Malaysia

Neonatal Nav1.5 (nNav1.5) has been known to potentiate breast cancer (BCa) metastasis. The detection of anti-nNav1.5 antibodies (anti-nNav1.5-Ab) reflects the immunogenicity of nNav1.5. However, the presences of circulating nNav1.5 antigen and anti-nNav1.5-Ab in the context of BCa metastasis hav...