Hyperglycaemia attenuated C2C12 myoblast proliferation and induced skeletal muscle atrophy via modulating myogenic regulatory factors genes expression in diabetic rats

• Main Authors: Chittipong Tipbunjong, Wipapan Khimmaktong, Chumpol Pholpramool, Piyaporn Surinlert
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2023
• Online Access: http://journalarticle.ukm.my/21532/1/S%204.pdf; http://journalarticle.ukm.my/21532/; http://www.ukm.my/jsm/index.html
• Institution: Universiti Kebangsaan Malaysia

Diabetes mellitus is characterised by high blood glucose level termed hyperglycaemia (HG). It has been reported to affect skeletal muscle by inducing skeletal muscle atrophy and skeletal muscle protein degradation leading to impairment of muscle function. This study aimed to investigate the effects...