In Vitro antimicrobial, antiglycolytic, and antibiofilm activities of synthetic 1,4-naphthoquinone derivatives against cariogenic bacteria

• Main Authors: Pichayaporn Ratti, Jutharat Manuschai, Jiraporn Kara, Luelak Lomlim, Supawadee Naorungroj
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2023
• Online Access: http://journalarticle.ukm.my/21545/1/S%2016.pdf; http://journalarticle.ukm.my/21545/; http://www.ukm.my/jsm/index.html
• Institution: Universiti Kebangsaan Malaysia

This study investigated the potential anticaries properties of synthetic 1,4-naphthoquinone derivatives. Synthetic 1,4-naphthoquinone derivatives (2-4) were designed and synthesized by employing lawsone methyl ether (LME, 1), a plant-derived 1,4-naphthoquinone, as a lead compound. The synthetic co...