RAD50 deficiency and its effects on zebrafish embryonic development and DNA repair mechanisms
The MRE11-RAD50-NBS1 (MRN) complex is essential in detecting, signaling, and repairing DNA double-strand breaks (DSBs), thus maintaining genomic integrity. Mutations in RAD50 are linked to severe conditions such as microcephaly, mental retardation, and growth retardation in humans. This study invest...
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Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Penerbit Universiti Kebangsaan Malaysia
2024
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Online Access: | http://journalarticle.ukm.my/24752/1/MAE%204.pdf http://journalarticle.ukm.my/24752/ https://jms.mabjournal.com/index.php/mab/issue/view/63 |
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Institution: | Universiti Kebangsaan Malaysia |
Language: | English |