The Evolution and Dissemination of Methicillin Resistance Determinant in Staphylococcus aureus
Staphylococcus aureus is an opportunistic pathogen and is frequently associated with the antimicrobial resistance. There has been horizontal gene transfer of Staphylococcus chromosome cassette mec (SCCmec) among the staphylococcal species that colonize a similar colonization niche, which eventual...
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Format: | Book Section |
Language: | English English |
Published: |
InTechOpen
2017
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Subjects: | |
Online Access: | http://eprints.unisza.edu.my/3536/1/FH05-FBIM-17-09489.pdf http://eprints.unisza.edu.my/3536/2/FH05-FBIM-17-09488.pdf http://eprints.unisza.edu.my/3536/ |
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Institution: | Universiti Sultan Zainal Abidin |
Language: | English English |
Summary: | Staphylococcus aureus is an opportunistic pathogen and is frequently associated with the
antimicrobial resistance. There has been horizontal gene transfer of Staphylococcus
chromosome cassette mec (SCCmec) among the staphylococcal species that colonize a
similar colonization niche, which eventually results in emergence of new variant with
enhanced survival ability in terms of antimicrobial resistance and virulence level in S.
aureus. Evolution and dissemination of SCCmec structure resulted in the emergence of
methicillin-resistant S. aureus (MRSA) clones around the world covering hospital,
community, and livestock settingsǯ MRSA also has the ability to resist different antibiotic
profiles known as multidrug-resistant S. aureus (MDR S. aureus). |
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