Caprine mammary protease-activated receptor 2 expressions with staphylococcus aureus and MRSA based mastitis

Mastitis is an inflammation of mammary glands resulting from imbalance interaction between the agent, the susceptible animal, and the environment [1,2]. Clinically, it is characterized by fever, warm, painful, and swollen mammary gland [3,4]. PAR2 a cell surface G protein- coupled receptor, plays...

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Bibliographic Details
Main Authors: Mohd Faizal, Ghazali, Siti Mariam, Zainal Ariffin
Format: Conference or Workshop Item
Language:English
Published: 2021
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Online Access:http://eprints.unisza.edu.my/4300/1/FH03-FBIM-21-54979.pdf
http://eprints.unisza.edu.my/4300/
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Institution: Universiti Sultan Zainal Abidin
Language: English
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Summary:Mastitis is an inflammation of mammary glands resulting from imbalance interaction between the agent, the susceptible animal, and the environment [1,2]. Clinically, it is characterized by fever, warm, painful, and swollen mammary gland [3,4]. PAR2 a cell surface G protein- coupled receptor, plays an important role in the induction and amplification of the inflammatory response through proteolytic cleavage by serine proteases [5]. In ruminants, increased protease activity has been observed in milk from mastitis animals [6]. The objective of this study was to quantify PAR2 mRNA expression in the healthy and inflamed mammary gland tissue of goats due to infection caused by S. aureus and MRSA.